3-Chloro-4-fluorophenylhydrazine Hydrochloride - CAS 175135-74-7

Name: 3-Chloro-4-fluorophenylhydrazine Hydrochloride
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB013077
Product Name:	3-Chloro-4-fluorophenylhydrazine Hydrochloride
CAS:	175135-74-7
Synonyms:	(3-chloro-4-fluorophenyl)hydrazine;hydrochloride; (3-chloro-4-fluorophenyl)hydrazine;hydrochloride

Technical Data

IUPAC Name:	(3-chloro-4-fluorophenyl)hydrazine;hydrochloride
Description:	3-Chloro-4-fluorophenylhydrazine Hydrochloride (CAS# 175135-74-7) is used to prepare 1,5- and 1,3-diaryl substituted pyrazoles as potential antimalarials targeting the enoyl-ACP reductase of Plasmodium falciparum.
Molecular Weight:	197.04
Molecular Formula:	C6H7Cl2FN2
Canonical SMILES:	C1=CC(=C(C=C1NN)Cl)F.Cl
InChI:	InChI=1S/C6H6ClFN2.ClH/c7-5-3-4(10-9)1-2-6(5)8;/h1-3,10H,9H2;1H
InChI Key:	DWCDDXINAZHRLK-UHFFFAOYSA-N
Boiling Point:	253.1 °C at 760 mmHg
MDL:	MFCD00052267
LogP:	3.34000

GHS Hazard Statement:	H302 (80%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation]
Precautionary Statement:	P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
WO-2015075051-A1	Allosteric inhibitors of atypical protein kinases c	20131119
US-2015203500-A1	Tris(hetero)arylpyrazoles and use thereof	20120817
US-9249148-B2	Tris(hetero)arylpyrazoles and use thereof	20120817
US-2015105388-A1	Carboxamide-substituted heteroaryl-pyrazoles and the use thereof	20111129
US-9296720-B2	Carboxamide-substituted heteroaryl-pyrazoles and the use thereof	20111129

Complexity:	112
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	2
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	195.9970318
Formal Charge:	0
Heavy Atom Count:	11
Hydrogen Bond Acceptor Count:	3
Hydrogen Bond Donor Count:	3
Isotope Atom Count:	0
Monoisotopic Mass:	195.9970318
Rotatable Bond Count:	1
Topological Polar Surface Area:	38
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0