3-Chloro-2-(hydroxymethyl)pyrazine - CAS 89283-32-9
Catalog: |
BB039402 |
Product Name: |
3-Chloro-2-(hydroxymethyl)pyrazine |
CAS: |
89283-32-9 |
Synonyms: |
(3-chloro-2-pyrazinyl)methanol; (3-chloropyrazin-2-yl)methanol |
IUPAC Name: | (3-chloropyrazin-2-yl)methanol |
Description: | 3-Chloro-2-(hydroxymethyl)pyrazine (CAS# 89283-32-9) is a useful reagent for the preparation of indazolylquinazolinones as inhibitors of human immunodeficiency virus replication. |
Molecular Weight: | 144.56 |
Molecular Formula: | C5H5ClN2O |
Canonical SMILES: | C1=CN=C(C(=N1)CO)Cl |
InChI: | InChI=1S/C5H5ClN2O/c6-5-4(3-9)7-1-2-8-5/h1-2,9H,3H2 |
InChI Key: | NYTVRJQDIXLFAT-UHFFFAOYSA-N |
Boiling Point: | 256 °C |
Density: | 1.422 g/cm3 |
Appearance: | Solid |
LogP: | 0.62230 |
Publication Number | Title | Priority Date |
WO-2020084492-A1 | Inhibitors of human immunodeficiency virus replication | 20181024 |
TW-202031261-A | Inhibitors of human immunodeficiency virus replication | 20181024 |
US-2020360384-A1 | Inhibitors of human immunodeficiency virus replication | 20181024 |
CN-113195475-A | Inhibitors of human immunodeficiency virus replication | 20181024 |
EP-3870577-A1 | Inhibitors of human immunodeficiency virus replication | 20181024 |
Complexity: | 91 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 144.0090405 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 144.0090405 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 46 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.1 |
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