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| Description: | 3-Bromo-4-iodo-1-(triisopropylsilyl)-1H-pyrrole is an intermediate for the synthesis of MS094 (M755450), which is a derivative of MS023 (M755443). MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues. |
| Molecular Weight: | 428.22 |
| Molecular Formula: | C13H23BrINSi |
| Solubility: | Chloroform |
| Appearance: | Blackish-Brown Coloured Solid |
| Storage: | 4°C |
| References: | Eram, Mohammad S., et al. ACS Chemical Biology,11, 772-(2016); Ferreira de Freitas, Renato., et al. J. Med. Chem., 59, 6838 (2016). |
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