3-Aminophthalimide - CAS 2518-24-3
Catalog: |
BB018786 |
Product Name: |
3-Aminophthalimide |
CAS: |
2518-24-3 |
Synonyms: |
4-aminoisoindole-1,3-dione |
IUPAC Name: | 4-aminoisoindole-1,3-dione |
Description: | 3-Aminophthalimide was used to study design and synthesis of Rho kinase inhibitors (I). |
Molecular Weight: | 162.15 |
Molecular Formula: | C8H6N2O2 |
Canonical SMILES: | C1=CC2=C(C(=C1)N)C(=O)NC2=O |
InChI: | InChI=1S/C8H6N2O2/c9-5-3-1-2-4-6(5)8(12)10-7(4)11/h1-3H,9H2,(H,10,11,12) |
InChI Key: | GQBONCZDJQXPLV-UHFFFAOYSA-N |
Boiling Point: | 447 °C |
Density: | 1.476 g/cm3 |
MDL: | MFCD00041853 |
LogP: | 1.06240 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P272, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P333+P313, P337+P313, P362, P363, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
JP-2020174673-A | Classification method of solid phase and virus with immobilized sugar chain | 20200630 |
CN-111349052-A | Synthesis method of mosapride citrate | 20200407 |
CN-111349052-B | Synthesis method of mosapride citrate | 20200407 |
WO-2021199031-A1 | Method of analyzing a single-cell western blot chip | 20200329 |
US-11008288-B1 | Methods for preparation of apremilast | 20191230 |
PMID | Publication Date | Title | Journal |
20414499 | 20100607 | Decarboxylative photorelease coupled with fluorescent up/down reporter function based on the aminophthalimide-serine system | Chemical communications (Cambridge, England) |
19645325 | 20090501 | Synthesis and anticonvulsant evaluation of some N-substituted phthalimides | Acta poloniae pharmaceutica |
19140729 | 20090201 | The use of 3-aminophthalimide as a pro-chemiluminescent label in chemiluminescence and fluorescence-based cellular assays | Bioconjugate chemistry |
16137884 | 20051015 | Design and synthesis of phthalimide-type histone deacetylase inhibitors | Bioorganic & medicinal chemistry letters |
Complexity: | 239 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 162.042927438 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 162.042927438 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 72.2 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.6 |
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