3-Amino-7-azaindazole - CAS 6752-16-5

Catalog:	BB033315
Product Name:	3-Amino-7-azaindazole
CAS:	6752-16-5
Synonyms:	2H-pyrazolo[3,4-b]pyridin-3-amine

Technical Data

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Computed Properties

IUPAC Name:	2H-pyrazolo[3,4-b]pyridin-3-amine
Description:	3-Amino-7-azaindazole (CAS# 6752-16-5) is a compound useful in organic synthesis.
Molecular Weight:	134.14
Molecular Formula:	C6H6N4
Canonical SMILES:	C1=CC2=C(NN=C2N=C1)N
InChI:	InChI=1S/C6H6N4/c7-5-4-2-1-3-8-6(4)10-9-5/h1-3H,(H3,7,8,9,10)
InChI Key:	LUAQTQAFUORQHV-UHFFFAOYSA-N
Boiling Point:	406.7 °C at 760 mmHg
Purity:	97.0 %
Density:	1.48 g/cm³
MDL:	MFCD04113611
LogP:	1.12130

Publication Number	Title	Priority Date
WO-2021005183-A1	Inhibitor of map kinase interacting serine/threonine kinase 1 (mnk1) and map kinase interacting serine/threonine kinase 2 (mnk2), cancer therapy and therapeutic combinations	20190710
CN-109503488-A	2- substituent methyl -4- substituted-amino methylphenol analog derivative and its medical usage	20181214
TW-202024071-A	Pyrazolo[3,4-b]pyridine compounds as inhibitors of tam and met kinases	20180830
AU-2019264078-A1	Novel heterocycle derivative	20180502
CN-107501306-B	Nine core zinc multifunctional crystal materials of one kind and preparation method thereof	20170911

PMID	Publication Date	Title	Journal
21699136	20110728	Selectivity of kinase inhibitor fragments	Journal of medicinal chemistry
12230249	20020501	Synthesis and antiproliferative activity in vitro of new 3-substituted aminopyrazolo[3,4-b]pyridines	Acta poloniae pharmaceutica
11512271	20010701	Synthesis and antiproliferative activity in vitro of new derivatives of 3-aminopyrazolo[3,4-b]pyridine. Part 1. Reaction of 3-aminopyrazolo[3,4-b]pyridine with 1,3-, 1,4-diketones and alpha,beta-unsaturated ketones	Archiv der Pharmazie

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Related Functional Groups

Amines and Anilines

[556-90-1]
Pseudothiohydantoin
[1232060-85-3]
(3R,4R)-4-Amino-3-methoxytetrahydropyran
[1006473-17-1]
[(2,3-Difluorophenyl)methyl][(1,3-dimethylpyrazol-4-yl)methyl]amine
[1106917-71-8]
[3-(Difluoromethoxy)phenyl]methanamine hydrochloride
[1951441-75-0]
2-(6-Methoxypyridin-2-yl)ethan-1-amine hydrochloride
[1431970-24-9]
2,2-Difluoro-N-[1-(1-methylpyrazol-4-yl)ethyl]ethanamine hydrochloride

Azaindazole

[1256833-42-7]
5-Fluoro-1H-pyrazolo[3,4-b]pyridine-3-carbonitrile
[937598-58-8]
1-(4-Fluorophenyl)-3,6-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carbohydrazide
[886503-31-7]
1,3-Dimethyl-6-(3-nitrophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
[937598-72-6]
1,3-Dimethyl-6-(4-methylphenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
[938018-19-0]
1,3-Dimethyl-6-(p-tolyl)-1H-pyrazolo[3,4-b]pyridine-4-carbohydrazide
[80537-07-1]
2-Phenylpyrazolo[1,5-a]pyridine-3-carboxylic acid

Indazoles

[885278-74-0]
Ethyl 1H-Indazole-7-carboxylate
[1171215-61-4]
Ethyl 2-[2-(1-ethylpyrazol-3-yl)benzimidazolyl]acetate
[590417-95-1]
6-Bromo-2-methyl-2H-indazole
[1956318-62-9]
3-Amino-5-[(3,5-difluorophenyl)difluoromethyl]-1H-indazole
[43120-28-1]
Methyl 1H-indazole-3-carboxylate
[885518-50-3]
4-Amino-6-bromo-1H-indazole

GHS Hazard Statement:	H301 (100%): Toxic if swallowed [Danger Acute toxicity, oral]
Precautionary Statement:	P264, P270, P301+P310, P321, P330, P405, and P501
Signal Word:	Danger

Complexity:	127
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	134.059246208
Formal Charge:	0
Heavy Atom Count:	10
Hydrogen Bond Acceptor Count:	3
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	134.059246208
Rotatable Bond Count:	0
Topological Polar Surface Area:	67.6 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	0.5