3-Amino-3-azabicyclo[3.3.0]octane hydrochloride - CAS 58108-05-7
Catalog: |
BB029936 |
Product Name: |
3-Amino-3-azabicyclo[3.3.0]octane hydrochloride |
CAS: |
58108-05-7 |
Synonyms: |
3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-amine;hydrochloride |
IUPAC Name: | 3,3a,4,5,6,6a-hexahydro-1H-cyclopenta[c]pyrrol-2-amine;hydrochloride |
Description: | 3-Amino-3-azabicyclo[3.3.0]octane hydrochloride (CAS# 58108-05-7) is used as a reactant in the synthesis of Gliclazide (G409875), a sulfonylurea hypoglycemic agent. Used as an antidiabetic. |
Molecular Weight: | 162.66 |
Molecular Formula: | C7H14N2 · HCl |
Canonical SMILES: | C1CC2CN(CC2C1)N.Cl |
InChI: | InChI=1S/C7H14N2.ClH/c8-9-4-6-2-1-3-7(6)5-9;/h6-7H,1-5,8H2;1H |
InChI Key: | WPYNXKFLSQEEFE-UHFFFAOYSA-N |
Boiling Point: | 229.9 °C at 760 mmHg |
MDL: | MFCD00792451 |
LogP: | 2.03220 |
Quality Standard: | - |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-112851563-A | Synthesis process of N-amino-3-azabicyclo [3,3,0] octane hydrochloride | 20201230 |
CN-110372568-A | A kind of crystallization and preparation method thereof of gliclazide intermediate | 20190822 |
WO-2020018970-A1 | Sulfonylurea compounds as inhibitors of interleukin-1 activity | 20180720 |
AU-2019305095-A1 | Sulfonylurea compounds as inhibitors of interleukin-1 activity | 20180720 |
TW-202019937-A | Sulfonylurea compounds as inhibitors of interleukin-1 activity | 20180720 |
Complexity: | 102 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 2 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 162.0923762 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 162.0923762 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 29.3 Å2 |
Undefined Atom Stereocenter Count: | 2 |
Undefined Bond Stereocenter Count: | 0 |
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Pyrrolidines
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