3-Amino-2,6-piperidinedione hydrochloride - CAS 24666-56-6
Catalog: |
BB018574 |
Product Name: |
3-Amino-2,6-piperidinedione hydrochloride |
CAS: |
24666-56-6 |
Synonyms: |
3-Amino-2,6-piperidinedione Monohydrochloride; 2-Amino-glutarimide Hydrochloride; 3-Amino-2,6-dioxopiperidine Hydrochloride; 3-Aminopiperidine-2,6-dione Monohydrochloride; DL-Glutamic Acid Imide Hydrochloride; Glutamimide Hydrochloride; 2,6-dioxopiperidine-3-ammonium chloride; Glutamic acid imide hydrochloride; Glutamic acid imide-DL-hydrochloride; ACMC-20a23n; (+-)-3-Amino-2,6-piperidinedione monohydrochloride; AMPD00004; 3-Aminopiperidine-2,6-dione, HCl |
Related CAS: | 2686-86-4 2353-44-8 (free base)
|
IUPAC Name: | 3-aminopiperidine-2,6-dione;hydrochloride |
Description: | 3-Aminopiperidine-2,6-dione hydrochloride is a reagent for preparing lenalidomide that can induce ubiquitination and degradation of CK1α in del(5q) MDS. It can also be used to prepare phthalimide conjugates that can promote ligand-dependent target protein degradation. |
Molecular Weight: | 164.59 |
Molecular Formula: | C5H9ClN2O2 |
Canonical SMILES: | C1CC(=O)NC(=O)C1N.Cl |
InChI: | InChI=1S/C5H8N2O2.ClH/c6-3-1-2-4(8)7-5(3)9;/h3H,1-2,6H2,(H,7,8,9);1H |
InChI Key: | YCPULGHBTPQLRH-UHFFFAOYSA-N |
Boiling Point: | 334.5 °C at 760 mmHg |
Melting Point: | > 208 °C (dec.) |
Purity: | > 99 % |
Solubility: | Soluble in Water; Slightly soluble in DMSO (Heated); Sparingly soluble in Methanol (Sonicated) |
Appearance: | White to off-white solid |
Storage: | 2-8 °C |
LogP: | 0.58140 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
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Complexity: | 155 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 2 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 164.0352552 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 3 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 164.0352552 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 72.2 Å2 |
Undefined Atom Stereocenter Count: | 1 |
Undefined Bond Stereocenter Count: | 0 |
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