3-Amino-2,2-difluoro-1-propanol - CAS 155310-11-5
Catalog: |
BB011108 |
Product Name: |
3-Amino-2,2-difluoro-1-propanol |
CAS: |
155310-11-5 |
Synonyms: |
3-amino-2,2-difluoro-1-propanol; 3-amino-2,2-difluoropropan-1-ol |
IUPAC Name: | 3-amino-2,2-difluoropropan-1-ol |
Description: | 3-Amino-2,2-difluoro-1-propanol (CAS# 155310-11-5) is a reactant used in the synthesis of pyridopyrimidine based cannabinoid-1 receptor inverse agonists. |
Molecular Weight: | 111.09 |
Molecular Formula: | C3H7F2NO |
Canonical SMILES: | C(C(CO)(F)F)N |
InChI: | InChI=1S/C3H7F2NO/c4-3(5,1-6)2-7/h7H,1-2,6H2 |
InChI Key: | IUZGHWSIJQTEAD-UHFFFAOYSA-N |
Appearance: | Low melting solid or clear liquid |
LogP: | 0.27300 |
GHS Hazard Statement: | H302 (50%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P260, P264, P270, P280, P301+P312, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P330, P363, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2021173523-A1 | Hot melt extruded solid dispersions containing a bcl2 inhibitor | 20200224 |
WO-2021158481-A1 | Substituted 1,1'-biphenyl compounds and methods using same | 20200203 |
WO-2021066873-A1 | Condensed heterocycles as bcl-2 inhibitors | 20191003 |
WO-2021060395-A1 | Sustained-release pharmaceutical composition | 20190925 |
WO-2020113233-A1 | Irak degraders and uses thereof | 20181130 |
Complexity: | 56.9 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 111.04957017 |
Formal Charge: | 0 |
Heavy Atom Count: | 7 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 111.04957017 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 46.2 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.7 |
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