3-Acetyl-2-chloropyridine - CAS 55676-21-6
Catalog: |
BB029124 |
Product Name: |
3-Acetyl-2-chloropyridine |
CAS: |
55676-21-6 |
Synonyms: |
Ethanone, 1-(2-chloro-3-pyridinyl)-; 1-(2-Chloro-3-pyridinyl)ethanone; 1-(2-Chloro-3-pyridyl)ethanone; 1-(2-Chloropyridin-3-yl)ethan-1-one; 2-Chloro-3-acetylpyridine |
IUPAC Name: | 1-(2-chloropyridin-3-yl)ethanone |
Description: | 3-acetyl-2-chloropyridine (CAS# 55676-21-6) is a reagent used in the synthesis of Volitinib, a highly potent and selective mesenchymal-epithelial transition factor (c-Met) inhibitor as an anti-cancer agent. |
Molecular Weight: | 155.58 |
Molecular Formula: | C7H6ClNO |
Canonical SMILES: | CC(=O)C1=C(N=CC=C1)Cl |
InChI: | InChI=1S/C7H6ClNO/c1-5(10)6-3-2-4-9-7(6)8/h2-4H,1H3 |
InChI Key: | WIWIOUAFBHZLNQ-UHFFFAOYSA-N |
Boiling Point: | 70°C |
Purity: | 95% |
Density: | 1.233±0.06 g/cm3 |
Appearance: | Colorless to Brown Clear Liquid |
Storage: | Store at RT under inert atmosphere |
MDL: | MFCD03840751 |
LogP: | 1.93760 |
GHS Hazard Statement: | H302 (93.02%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-112047941-A | Compound and application thereof in preparing medicine for treating diseases caused by high expression of Flt3/c-Met kinase | 20200914 |
CN-110117246-A | A kind of preparation method of 3- indoles pimelie kelone compounds | 20190618 |
WO-2020132603-A2 | Salicyl-adenosinemonosulfamate analogs and uses thereof | 20181221 |
JP-2019011367-A | Method for producing optically active secondary alcohol | 20181012 |
US-2019382402-A1 | Indazole containing macrocycles and therapeutic uses thereof | 20180615 |
Complexity: | 138 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 155.0137915 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 155.0137915 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 30 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.5 |
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Related Functional Groups
Carbonyl Compounds
Pyridines
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