Description: | 3,4-Difluoro-1,5-dioxaspiro[5.5]undecan-2-one is an intermediate in the synthesis of Fluoromalonaldehydic Acid (F592600), a degradation product of 2,2'-Anhydro-1-β-D-arabinofuranosyl-5-fluorocytosine and 1-β-D-Arabinofuranosyl-5-fluorocytosine in rats. Fluoromalonaldehydic acid would be oxidized in vivo to fluoromalonic acid and utimately to fluoroacetate, compounds known to inhibit the Krebs cycle. |
Molecular Weight: | 206.19 |
Molecular Formula: | C9H12F2O3 |
References: | Chou, T.-C., et al. Cancer Treat. Reports, 61, 617 (1977),. |
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