3,4-Di(3-indolyl)-1H-pyrrole-2,5-dione - CAS 119139-23-0

Catalog: BB004414
Product Name: 3,4-Di(3-indolyl)-1H-pyrrole-2,5-dione
CAS: 119139-23-0
Synonyms: 3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione; 3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione
3,4-Di(3-indolyl)-1H-pyrrole-2,5-dione
IUPAC Name:3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione
Description:Bisindolylmaleimide IV (BIM IV) is an inhibitor of pyruvate phosphate dikinase (PPDK). It is a cell-permeable potent and somewhat selective inhibitor of PKC with IC50 of 87 nM. BIM IV is a cell-permeable inhibitor of protein kinase C (PKC) with IC50 values reported to range from 0.10 to 0.55 µM. It also inhibits protein kinase A (PKA) with an IC50 of 2.7 μM.
Molecular Weight:327.34
Molecular Formula:C20H13N3O2
Canonical SMILES:C1=CC=C2C(=C1)C(=CN2)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54
InChI:InChI=1S/C20H13N3O2/c24-19-17(13-9-21-15-7-3-1-5-11(13)15)18(20(25)23-19)14-10-22-16-8-4-2-6-12(14)16/h1-10,21-22H,(H,23,24,25)
InChI Key:DQYBRTASHMYDJG-UHFFFAOYSA-N
Boiling Point:690.1 °C at 760 mmHg (Predicted)
Melting Point:296.19 °C (Predicted)
Flash Point:371.2±31.5 °C
Purity:> 98 %
Density:1.486 g/cm3
Solubility:Soluble in DMSO.
Appearance:Crystalline solid
Storage:Powder:
-20°C 3 years
4°C 2 years
In solvent:
-80°C 6 months
-20°C 1 months
MDL:MFCD00236432
LogP:3.54520
Vapor Pressure:0.0±2.2 mmHg at 25°C

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