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| Description: | 3,4,5-Tris(pivaloxy) 6-Hydroxymethyl Canagliflozin is an intermediate in the synthesis of Canagliflozin Dimer (C175225), a dimer impurity of Canagliflozin (C175190); a sodium/glucose cotransporter 2 (SGLT2) inhibitor. Canagliflozin has been shown to dose dependently reduce calculated renal threshold for glucose excretion and increase urinary glucose excretion. Canagliflozin is a candidate for the treatment of type 2 diabetes and obesity. |
| Molecular Weight: | 696.87 |
| Molecular Formula: | C39H49FO8S |
| Solubility: | Chloroform; Dichloromethane; Ethyl Acetate |
| Appearance: | white solid |
| References: | Chao, E. et al. Drug Fut., 36, 351 (2011); Sha, S. et al. Diab. Obes. Metab., 13, 669 (2011); Kipnes, M.S. Clin. Invest., 1, 145 (2011). |
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