IUPAC Name: | 3-[2-(dimethylamino)ethoxy]anilinedihydrochloride |
Description: | 3-[[2-(Dimethylamino)ethyl]oxy]aniline Dihydrochloride is used in the preparation of thiazole and oxazole kinase inhibitors for cancer treatment. It is also used in the preparation of imidazopyridines as inhibitors of IGF- 1R and IR and one or both of EGFR and ErbB2 kinases for treating neoplasm. |
Molecular Weight: | 180.25 + 2(36.46) |
Molecular Formula: | C10H16N2O·2HCl |
Canonical SMILES: | CN(C)CCOC1=CC=CC(=C1)N.Cl.Cl |
InChI: | InChI=1S/C10H16N2O.2ClH/c1-12(2)6-7-13-10-5-3-4-9(11)8-10/h3-5,8H,6-7,11H2,1-2H32*1H |
InChI Key: | UWUWTAXZZBMJDS-UHFFFAOYSA-N |
References: | Adjabeng, G., et. al. PCT Int. Appl., 301 pp. (2009); Kuntz, K., et. al. U.S. Pat. Appl. Publ., 249 pp. (2008). |
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