3-[1-(Dimethylamino)ethyl]phenyl Ethyl(methyl)carbamate - CAS 105601-20-5

Name: 3-[1-(Dimethylamino)ethyl]phenyl Ethyl(methyl)carbamate
Brand: BOC Sciences
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Catalog:	BB001674
Product Name:	3-[1-(Dimethylamino)ethyl]phenyl Ethyl(methyl)carbamate
CAS:	105601-20-5
Synonyms:	N-ethyl-N-methylcarbamic acid [3-[1-(dimethylamino)ethyl]phenyl] ester; [3-[1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate

Technical Data

IUPAC Name:	[3-[1-(dimethylamino)ethyl]phenyl] N-ethyl-N-methylcarbamate
Description:	3-[1-(Dimethylamino)ethyl]phenyl Ethyl(methyl)carbamate (CAS# 105601-20-5) is a brain selective acetylcholinesterase inhibitor. Nootropic.
Molecular Weight:	250.34
Molecular Formula:	C14H22N2O2
Canonical SMILES:	CCN(C)C(=O)OC1=CC=CC(=C1)C(C)N(C)C
InChI:	InChI=1S/C14H22N2O2/c1-6-16(5)14(17)18-13-9-7-8-12(10-13)11(2)15(3)4/h7-11H,6H2,1-5H3
InChI Key:	XSVMFMHYUFZWBK-UHFFFAOYSA-N
LogP:	2.75970

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PMID	Publication Date	Title	Journal
32092302	20200301	An in vitro study on the interaction of the anti-Alzheimer drug rivastigmine with human erythrocytes	Chemico-biological interactions
29739252	20181201	Evaluation of the rivastigmine role against botulinum toxin-A-induced osteoporosis in albino rats: A biochemical, histological, and immunohistochemical study	Human & experimental toxicology
29777723	20180801	Effect of acetylcholinesterase inhibitors donepezil and rivastigmine on the activity and expression of cyclooxygenases in a model of the inflammatory action of fluoride on macrophages obtained from THP-1 monocytes	Toxicology
23728651	20130531	Rivastigmine for vascular cognitive impairment	The Cochrane database of systematic reviews
23123248	20130325	Inhibition of human carboxylesterases hCE1 and hiCE by cholinesterase inhibitors	Chemico-biological interactions

Complexity:	269
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	250.168127949
Formal Charge:	0
Heavy Atom Count:	18
Hydrogen Bond Acceptor Count:	3
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	250.168127949
Rotatable Bond Count:	5
Topological Polar Surface Area:	32.8
Undefined Atom Stereocenter Count:	1
Undefined Bond Stereocenter Count:	0
XLogP3:	2.3