((2S,4R)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate
Catalog: |
BB069928 |
Product Name: |
((2S,4R)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate |
Description: | ((2S,4R)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate is an intermediate in the synthesis of Itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal. |
Molecular Weight: | 451.75 |
Molecular Formula: | C18H17Cl3O5S |
Solubility: | DCM, Ethyl Acetate, Methanol |
Appearance: | Colourless Oil |
References: | Heykants, J., et al. Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al. Curr. Clin. Top. Infect. Dis., 13, 74 (1993). |
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