(2R)-Tetrahydro-2-furanmethanamine Hydrochloride - CAS 7175-80-6
Catalog: |
BB076744 |
Product Name: |
(2R)-Tetrahydro-2-furanmethanamine Hydrochloride |
CAS: |
7175-80-6 |
Synonyms: |
(R)-Tetrahydro-2-furanmethanamine Hydrochloride; (R)-Tetrahydro-furfurylamine Hydrochloride; (-)-(R)-Tetrahydrofurfurylamine Hydrochloride; (2R)-2-Aminomethyltetrahydrofuran Hydrochloride; (2R)-Tetrahydrofuran-2-methanamine Hydrochloride; (R)-(-)-Tetrahydrofurfurylamine Hydrochloride; (R)-(Tetrahydrofuran-2-yl)methanamine Hydrochloride; (R)-1-(Tetrahydrofuran-2-yl)methylamine Hydrochloride; (R)-Tetrahydrofurfurylamine Hydrochloride; [((R)-Tetrahydrofuran-2-yl)methyl]amine Hydrochloride; [(R)-1-(Tetrahydro-furan-2-yl)]-methylamine Hydrochloride; [[(2R)-Tetrahydro-2-furanyl]methyl]amine Hydrochloride |
IUPAC Name: | [(2R)-oxolan-2-yl]methanaminehydrochloride |
Description: | (2R)-Tetrahydro-2-furanmethanamine is a stereoisomer of Tetrahydro-2-furanmethanamine (T293545) which is used in the synthesis of novel topoisomerase I targeting anti-cancer agents with mild to potent cytotoxic activity. Tetrahydro-2-furanmethanamine (T293545) is also used in the discovery and synthesis of orally bioavailable stearoyl-CoA desaturase 1 inhibitors. |
Molecular Weight: | 101.15 + 36.46 |
Molecular Formula: | C5H11NO·HCl |
Canonical SMILES: | C1CC(OC1)CN.Cl |
InChI: | InChI=1S/C5H11NO.ClH/c6-4-5-2-1-3-7-5/h5H,1-4,6H21H/t5-/m1./s1 |
InChI Key: | TUXSUKLRDNJDOR-NUBCRITNSA-N |
Melting Point: | 106-108°C |
Solubility: | Chloroform (Slightly), DMSO (Slightly) |
Appearance: | White to Pale Grey Solid |
Storage: | Hygroscopic, Refrigerator, under inert atmosphere |
References: | Lopez-Rodriguez, M. et al. 44, 4504 (2001); Liu, G. et al. J. Med. Chem., 50, 3086 (2007). |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P264+P265, P271, P280, P302+P352, P304+P340, P305+P351+P338, P319, P321, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Signal Word: | Warning |
Complexity: | 56 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 2 |
Defined Atom Stereocenter Count: | 1 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 137.0607417 |
Formal Charge: | 0 |
Heavy Atom Count: | 8 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 137.0607417 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 35.2Ų |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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