(2R)-Ethylpyrrolidine Hydrochloride - CAS 460748-80-5

Catalog:	BB066042
Product Name:	(2R)-Ethylpyrrolidine Hydrochloride
CAS:	460748-80-5
Synonyms:	(2R)-2-Ethylpyrrolidine Hydrochloride

Technical Data

IUPAC Name:	(2R)-2-ethylpyrrolidinehydrochloride
Description:	(2R)-Ethylpyrrolidine Hydrochloride is used as a reagent in the synthesis of 6-(4-pyrimidinyl)-1H-indazole derivatives as PDK1 kinase inhibitors useful in treatment of cancer, immune, metabolic and other kinase-mediated diseases. Also used as a reagent in the synthesis of aryloxazole derivatives as histamine H3 receptor antagonists or inverse agonists.
Molecular Weight:	135.64
Molecular Formula:	C6H14ClN
Canonical SMILES:	CCC1CCCN1.Cl
InChI:	InChI=1S/C6H13N.ClH/c1-2-6-4-3-5-7-6/h6-7H,2-5H2,1H31H/t6-/m1./s1
InChI Key:	LKNCADZJRBHOFP-FYZOBXCZSA-N
References:	Axten, J.M., et al. PCT Int. Appl. WO 2010059658 A1 20100527. May 27, 2010; Beavers, L.S., et al. PCT Int. Appl. WO 2006019833 A1 20060223. Feb 23, 2006.

Complexity:	52.1
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	2
Defined Atom Stereocenter Count:	1
Defined Bond Stereocenter Count:	0
Exact Mass:	135.0814771
Formal Charge:	0
Heavy Atom Count:	8
Hydrogen Bond Acceptor Count:	1
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	135.0814771
Rotatable Bond Count:	1
Topological Polar Surface Area:	12Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0