Description: | (2R,4S)-4-Amino-2-hydroxy-2,6-dimethyl-3-oxoheptyl Acetate Trifluoroacetic Acid Salt is an intermediate for the synthesis of Carfilzomib (2R,4S)-Diol (C183470), which is a derivative of Carflizomib (C183460), a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma. |
Molecular Weight: | 231.29 + 114.02 |
Molecular Formula: | C11H21NO4· |
Solubility: | Chloroform |
Appearance: | Colorless Oil |
Storage: | -20°C |
References: | Fostier, K., et al. Oncotargets. Therap., 5, 237 (2012); Geurink, P.P., et al. J. Med. Chem., 56, 1262 (2013); McCormack, P.L., et al. Drugs., 72, 2023 (2012). |
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