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((2R,4R)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate

((2R,4R)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate

Catalog:	BB069926
Product Name:	((2R,4R)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate

Technical Data

Description:	((2R,4R)-2-(Chloromethyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methyl 4-Methylbenzenesulfonate is an intermediate in the synthesis of Itraconazole (I937500), an orally active antimycotic structurally related to Ketoconazole. Antifungal.
Molecular Weight:	451.75
Molecular Formula:	C18H17Cl3O5S
Solubility:	DCM, Ethyl Acetate, Methanol
Appearance:	Colourless Oil
References:	Heykants, J., et al. Mycoses, 32, Suppl 1, 67 (1989), Sugar, A.M.,et al. Curr. Clin. Top. Infect. Dis., 13, 74 (1993).

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