(2R,3S)-3-Hydroxynorleucine - CAS 59286-25-8

Catalog:	BB056256
Product Name:	(2R,3S)-3-Hydroxynorleucine
CAS:	59286-25-8
Synonyms:	(3S)-3-Hydroxy-D-norleucine; threo-3-Hydroxy-D-norleucine; (2R,3S)-2-amino-3-hydroxy-hexanoic Acid

Technical Data

IUPAC Name:	(2R,3S)-2-amino-3-hydroxyhexanoic acid
Description:	(2R,3S)-3-Hydroxynorleucine is an analogue of DL-6-Hydroxy Norleucine (H948855) which is an intermediate for antiviral and antihypertensive drugs.
Molecular Weight:	147.17
Molecular Formula:	C6H13NO3
Canonical SMILES:	CCCC(C(C(=O)O)N)O
InChI:	InChI=1S/C6H13NO3/c1-2-3-4(8)5(7)6(9)10/h4-5,8H,2-3,7H2,1H3,(H,9,10)/t4-,5+/m0/s1
InChI Key:	ONTYPWROJNTIRE-CRCLSJGQSA-N
Melting Point:	>153°C (dec.)
Solubility:	Water (Slightly)
Appearance:	White to Off-White Solid
Storage:	Refrigerator
References:	Kaufman, S., et al. J. Biol. Chem., 257, 14667 (1982), Hanson, R., et al. Bioorg. Chem., 18, 116 (1990), Oshima, T., et al. J. Bacteriol., 173, 3943 (1991), Oshima, T., et al. Eur. J. Biochem., 222, 305 (1994), Robl, J., et al. J. Med. Chem., 40, 1570 (1997).

Complexity:	116
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	2
Defined Bond Stereocenter Count:	0
Exact Mass:	147.08954328
Formal Charge:	0
Heavy Atom Count:	10
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	3
Isotope Atom Count:	0
Monoisotopic Mass:	147.08954328
Rotatable Bond Count:	4
Topological Polar Surface Area:	83.6Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	-2.1