23-Des(methoxyimino)-23-hydroxy Moxidectin O-TBS - CAS 112124-92-2

Catalog: BB068429
Product Name: 23-Des(methoxyimino)-23-hydroxy Moxidectin O-TBS
CAS: 112124-92-2
Synonyms: [6R,23S,25S(E)]-5-O-Demethyl-28-deoxy-25-(1,3-dimethyl-1-butenyl)-5-O-[(1,1-dimethylethyl)dimethylsilyl]-6,28-epoxy-23-hydroxy Milbemycin B; Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2'-[2H]pyran] Milbemycin B Deriv.
Description:23-Des(methoxyimino)-23-hydroxy Moxidectin O-TBS is an intermediate used in the synthesis of (I2,3S)-23-des(methoxyimino)-23-[(methylsulfanyl)methoxy]moxidectin (D292840), which is an impurity of moxidectin (M744800), a macrocyclic lactone and semisynthetic derivative of nemadectin. Moxidectin is a parasiticide used for the prevention and control of heartworm and intestinal worms. Moxidectin is found in veterinary medicine used to treat animals such as dogs, cats, horses, cattle and sheep.
Molecular Weight:727.05
Molecular Formula:C42H66O8Si
References:Bisset, S.A. et al. New Zeal. Vet. J., 40, 97 (1992); Monahan, C.M. et al. Vet. Parasitol., 63, 225 (1996); Glickman, L.T. et al. Int. J. Appl. Res. Vet. Med., 3, 49 (2005).

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