mPEG7-bromide - CAS 104518-25-4

Name: mPEG7-bromide
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB001408
Product Name:	mPEG7-bromide
CAS:	104518-25-4
Synonyms:	m-PEG7-Br; 22-Bromo-2,5,8,11,14,17,20-heptaoxadocosane; Bromo-PEG7-methoxy; m-PEG7-bromide; 2,5,8,11,14,17,20-Heptaoxadocosane, 22-bromo-; 1-bromo-2-(2-(2-(2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethane; Methoxy hepta(ethylene glycol)bromide

Technical Data

IUPAC Name:	1-[2-[2-[2-[2-[2-(2-bromoethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-2-methoxyethane
Description:	mPEG7-bromide is a PEG linker containing a bromide group. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
Molecular Weight:	403.31
Molecular Formula:	C15H31BrO7
Canonical SMILES:	COCCOCCOCCOCCOCCOCCOCCBr
InChI:	InChI=1S/C15H31BrO7/c1-17-4-5-19-8-9-21-12-13-23-15-14-22-11-10-20-7-6-18-3-2-16/h2-15H2,1H3
InChI Key:	YUFIIJSCVFVGJO-UHFFFAOYSA-N
Boiling Point:	424.9±40.0 °C at 760 mmHg
Purity:	>96%
Density:	1.208±0.06 g/cm3
Appearance:	Pale Yellow or Colorless Oily Liquid
Storage:	Sealed in dry, 2-8 °C
LogP:	1.12730

Publication Number	Title	Priority Date
WO-2019058387-A1	IMPROVED PROCESS FOR THE PREPARATION OF (5Î', 6Î') -17-ALLYL-6- (2,5,8,11,14,17,20-HEPTAOXADOCOSAN-22-YLOXY) -4,5-EPOXYMORPHINANE-3,14-DIOL AND ITS PHARMACEUTICALLY ACCEPTABLE SALTS	20170919
US-2020253955-A1	Naloxegol Oxalate and Solid Dispersion thereof	20161123
US-11077103-B2	Naloxegol oxalate and solid dispersion thereof	20161123
EP-3402782-B1	8-amino-2-oxo-1,3-diaza-spiro-[4.5]-decane derivatives	20160113

Complexity:	210
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	402.12532
Formal Charge:	0
Heavy Atom Count:	23
Hydrogen Bond Acceptor Count:	7
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	402.12532
Rotatable Bond Count:	20
Topological Polar Surface Area:	64.6
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	0