2-(trans-4-Aminocyclohexyl)acetonitrile - CAS 1266328-42-0
Catalog: |
BB006621 |
Product Name: |
2-(trans-4-Aminocyclohexyl)acetonitrile |
CAS: |
1266328-42-0 |
Synonyms: |
2-(4-aminocyclohexyl)acetonitrile; 2-(4-aminocyclohexyl)acetonitrile |
IUPAC Name: | 2-(4-aminocyclohexyl)acetonitrile |
Description: | (trans-4-Aminocyclohexyl)acetonitrile Hydrochloride was studied to prepare imidazopyridine derivatives as therapeutic JAK inhibitors. |
Molecular Weight: | 138.21 |
Molecular Formula: | C8H14N2 |
Canonical SMILES: | C1CC(CCC1CC#N)N |
InChI: | InChI=1S/C8H14N2/c9-6-5-7-1-3-8(10)4-2-7/h7-8H,1-5,10H2 |
InChI Key: | DZFWURNOMGMOCH-UHFFFAOYSA-N |
MDL: | MFCD27942777 |
LogP: | 2.11788 |
Publication Number | Title | Priority Date |
US-2019315712-A1 | Bicyclic carboxamides and methods of use thereof | 20180417 |
WO-2019204523-A1 | Bicyclic carboxamides and methods of use thereof | 20180417 |
US-10968201-B2 | Bicyclic carboxamides and methods of use thereof | 20180417 |
EP-3568396-B1 | Novel amino-imidazopyridine derivatives as janus kinase inhibitors and pharmaceutical use thereof | 20170111 |
US-2019177321-A1 | Small Molecule Inhibitors of the JAK Family of Kinases | 20161216 |
Complexity: | 137 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 138.115698455 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 138.115698455 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 49.8 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.5 |
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