2-Quinolinecarbonitrile - CAS 1436-43-7
Catalog: |
BB009638 |
Product Name: |
2-Quinolinecarbonitrile |
CAS: |
1436-43-7 |
Synonyms: |
quinoline-2-carbonitrile |
IUPAC Name: | quinoline-2-carbonitrile |
Description: | 2-Quinolinecarbonitrile (CAS# 1436-43-7) is a useful research chemical. |
Molecular Weight: | 154.17 |
Molecular Formula: | C10H6N2 |
Canonical SMILES: | C1=CC=C2C(=C1)C=CC(=N2)C#N |
InChI: | InChI=1S/C10H6N2/c11-7-9-6-5-8-3-1-2-4-10(8)12-9/h1-6H |
InChI Key: | WDXARTMCIRVMAE-UHFFFAOYSA-N |
Boiling Point: | 160 °C / 23 mmHg |
Density: | 1.21 g/cm3 |
MDL: | MFCD00134341 |
LogP: | 2.10648 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P312, P304+P340, P305+P351+P338, P312, P321, P322, P330, P332+P313, P337+P313, P362, P363, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-112625024-A | Amphiphilic fluorescent probe for rapid wash-free imaging of cell membrane | 20201126 |
CN-112710838-A | Application of quinolinecarbonitrile derivative in protein detection by protein imprinting method and preparation method thereof | 20201126 |
CN-111978248-A | Multi-site modifiable aggregation-induced emission quinoline nitrile derivative, and preparation method and application thereof | 20200807 |
WO-2021160087-A1 | Quinolyl phosphine oxide compound, and composition and application thereof | 20200214 |
US-2021147386-A1 | Pyrrolidine and piperidine compounds | 20191106 |
PMID | Publication Date | Title | Journal |
22179664 | 20120215 | Phase I study of bosutinib, a src/abl tyrosine kinase inhibitor, administered to patients with advanced solid tumors | Clinical cancer research : an official journal of the American Association for Cancer Research |
22214395 | 20120209 | Structure-activity relationships of cyanoquinolines with corrector-potentiator activity in ΔF508 cystic fibrosis transmembrane conductance regulator protein | Journal of medicinal chemistry |
21730204 | 20111001 | Cyanoquinolines with independent corrector and potentiator activities restore ΔPhe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis | Molecular pharmacology |
21588937 | 20101009 | 2-Cyano-quinolin-1-ium nitrate | Acta crystallographica. Section E, Structure reports online |
21588923 | 20101002 | 2-Cyano-quinolin-1-ium hydrogen sulfate | Acta crystallographica. Section E, Structure reports online |
Complexity: | 203 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 154.053098200 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 154.053098200 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 36.7 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.6 |
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