2-methylquinoline-4,6-diamine Dihydrochloride Salt

Catalog: BB056599
Product Name: 2-methylquinoline-4,6-diamine Dihydrochloride Salt
Description:2-methylquinoline-4,6-diamine Dihydrochloride Salt is an intermediate in the synthesis of NSC 23766 (N900280), which is a highly soluble and membrane permeable Rac GTPase inhibitor. NSC 23766 inhibits Rac GTPase by targeting Rac activation by guanine nucleotide exchange factor (GEF). NSC 23766 has been shown to inhibit the anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.
Molecular Weight:280.33 + 2(36.46)
Molecular Formula:C15H16N6·2HCl
Solubility:Methanol; Water
Appearance:Off-White Solid
References:Gao, Y., et. al. Proc. Natl. Acad. Sci. U.S.A., 101, 7618, (2004); Akbar, H., et. al. Methods Enzymol, 406, 554 (2006).

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