2-Methylpyridine-5-boronic Acid - CAS 659742-21-9
Catalog: |
BB032871 |
Product Name: |
2-Methylpyridine-5-boronic Acid |
CAS: |
659742-21-9 |
Synonyms: |
(6-methyl-3-pyridinyl)boronic acid; (6-methylpyridin-3-yl)boronic acid |
IUPAC Name: | (6-methylpyridin-3-yl)boronic acid |
Description: | 2-Methylpyridine-5-boronic Acid (CAS# 659742-21-9) is used in the preparation of various biologically active compound such as phosphoinositide-3-kinases (PI3K) and c-jun N-terminal kinase (JNK) inhibitors. |
Molecular Weight: | 136.94 |
Molecular Formula: | C6H8NO2B |
Canonical SMILES: | B(C1=CN=C(C=C1)C)(O)O |
InChI: | InChI=1S/C6H8BNO2/c1-5-2-3-6(4-8-5)7(9)10/h2-4,9-10H,1H3 |
InChI Key: | MZUSCPDSQJSBSY-UHFFFAOYSA-N |
Boiling Point: | 294.7 °C at 760 mmHg |
Flash Point: | Not applicable |
Density: | 1.18 g/cm3 |
MDL: | MFCD06801736 |
LogP: | -0.93020 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-112778294-A | 5-aminoisoxazole derivative and application thereof in preparation of multi-kinase inhibitor | 20210107 |
CN-113321645-A | 5-aminoisoxazole derivative and application thereof in preparation of multi-kinase inhibitor | 20210107 |
WO-2021201036-A1 | Hydroxypyrrolidine derivative and medicinal application thereof | 20200331 |
US-2021214366-A1 | Bicyclic heterocycles as fgfr inhibitors | 20200115 |
WO-2021146424-A1 | Bicyclic heterocycles as fgfr inhibitors | 20200115 |
Complexity: | 110 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 137.0648087 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 137.0648087 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 53.4 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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