2-Iodo-3-hydroxypyridine - CAS 40263-57-8
Catalog: |
BB024406 |
Product Name: |
2-Iodo-3-hydroxypyridine |
CAS: |
40263-57-8 |
Synonyms: |
2-iodopyridin-3-ol |
IUPAC Name: | 2-iodopyridin-3-ol |
Description: | 2-Iodo-3-hydroxypyridine acts as a reagent in the synthesis of the differentiating antibiotic azatyrosine. |
Molecular Weight: | 221.00 |
Molecular Formula: | C5H4INO |
Canonical SMILES: | C1=CC(=C(N=C1)I)O |
InChI: | InChI=1S/C5H4INO/c6-5-4(8)2-1-3-7-5/h1-3,8H |
InChI Key: | HJBGMPCMSWJZNH-UHFFFAOYSA-N |
Boiling Point: | 296.6 °C at 760 mmHg |
Density: | 2.142 g/cm3 |
MDL: | MFCD00023421 |
LogP: | 1.39180 |
GHS Hazard Statement: | H302 (86.36%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
TW-202039436-A | Inhibitors of tgf-beta r1 (alk5) useful to treat cell proliferation disorders | 20181227 |
WO-2020139636-A1 | (pyridin-2-yl)amine derivatives as tgf-beta r1 (alk5) inhibitors for the treatment of cancer | 20181227 |
CN-113348167-A | (pyridin-2-yl) amine derivatives as TGF-beta R1(ALK5) inhibitors for the treatment of cancer | 20181227 |
KR-20210110316-A | (pyridin-2-yl)amine derivatives as TGF-beta R1 (ALK5) inhibitors for the treatment of cancer | 20181227 |
BR-112020020196-A2 | compounds aimed at brm and associated methods of use | 20180401 |
PMID | Publication Date | Title | Journal |
21583269 | 20090529 | 2-Iodo-3-nitro-pyridine | Acta crystallographica. Section E, Structure reports online |
Complexity: | 78.8 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 220.93376 |
Formal Charge: | 0 |
Heavy Atom Count: | 8 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 220.93376 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 33.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.2 |
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