Description: | 2-Hydroxy Atorvastatin tert-Butyl Ester-d5 is an intermediate in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia. |
Molecular Weight: | 635.78 |
Molecular Formula: | C37H38D5FN2O6 |
References: | Kearney, A.S., et al. Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al. Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al. Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000). |
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