2-Hydroxy Atorvastatin tert-Butyl Ester-d5

Catalog: BB061166
Product Name: 2-Hydroxy Atorvastatin tert-Butyl Ester-d5
Synonyms: (3R,5R)-tert-Butyl 7-(2-(4-Fluorophenyl)-4-((2-hydroxyphenyl)carbamoyl)-5-isopropyl-3-phenyl-d5-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate
Description:2-Hydroxy Atorvastatin tert-Butyl Ester-d5 is an intermediate in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase inhibitor. Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
Molecular Weight:635.78
Molecular Formula:C37H38D5FN2O6
References:Kearney, A.S., et al. Pharm. Res., 10, 1461 (1993); Heinonen, T.M., et al. Clin. Ther., 18, 853 (1996); Whitfield, L.R., et al. Eur. J. Drug Metab. Pharmacokinet., 25, 97 (2000).

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