2-Hydroxy-4-methoxy-5-nitropyridine - CAS 607373-82-0
Catalog: |
BB030790 |
Product Name: |
2-Hydroxy-4-methoxy-5-nitropyridine |
CAS: |
607373-82-0 |
Synonyms: |
4-methoxy-5-nitro-1H-pyridin-2-one; 4-methoxy-5-nitro-1H-pyridin-2-one |
IUPAC Name: | 4-methoxy-5-nitro-1H-pyridin-2-one |
Description: | 2-Hydroxy-4-methoxy-5-nitropyridine (CAS# 607373-82-0) is used in the preparation of Rho-Kinase inhibitors that display antihypertensive activity. Also it is used in the preparation of aminofurans as potent inhibitors of AKT kinase. |
Molecular Weight: | 170.12 |
Molecular Formula: | C6H6N2O4 |
Canonical SMILES: | COC1=CC(=O)NC=C1[N+](=O)[O-] |
InChI: | InChI=1S/C6H6N2O4/c1-12-5-2-6(9)7-3-4(5)8(10)11/h2-3H,1H3,(H,7,9) |
InChI Key: | BBXOGUKAXIFZAE-UHFFFAOYSA-N |
Boiling Point: | 439 °C at 760 mmHg |
Density: | 1.454 g/cm3 |
Appearance: | Solid |
MDL: | MFCD07367779 |
LogP: | 1.22720 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
WO-2019243303-A1 | Pyridinyl and pyrazinyl-(aza)indolsulfonamides | 20180619 |
TW-202016088-A | Pyridyl and pyryl-(nitrogen) indosulfonamide | 20180619 |
AU-2019289788-A1 | Pyridinyl and pyrazinyl-(aza)indolsulfonamides | 20180619 |
CN-112469710-A | Pyridyl and pyrazinyl- (aza) indole sulfonamides | 20180619 |
EP-3810591-A1 | Pyridinyl and pyrazinyl-(aza)indolsulfonamides | 20180619 |
Complexity: | 286 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 170.03275668 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 170.03275668 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 84.2 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.6 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Nitrogen Compounds
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS