2-Fluoroadenine - CAS 700-49-2

Catalog:	BB034056
Product Name:	2-Fluoroadenine
CAS:	700-49-2
Synonyms:	2-fluoro-7H-purin-6-amine

Technical Data

Safety and Hazards

Patents

Literatures

Computed Properties

IUPAC Name:	2-fluoro-7H-purin-6-amine
Description:	2-Fluoroadenine (CAS# 700-49-2) is a useful research chemical.
Molecular Weight:	153.12
Molecular Formula:	C5H4FN5
Canonical SMILES:	C1=NC2=C(N1)C(=NC(=N2)F)N
InChI:	InChI=1S/C5H4FN5/c6-5-10-3(7)2-4(11-5)9-1-8-2/h1H,(H3,7,8,9,10,11)
InChI Key:	WKMPTBDYDNUJLF-UHFFFAOYSA-N
Boiling Point:	676.9 °C at 760 mmHg
Melting Point:	>350 °C
Purity:	95 %
Density:	1.739 g/cm³
Appearance:	White to light yellow crystal powder
Storage:	Refrigerator
MDL:	MFCD01632749
LogP:	0.65540

Publication Number	Title	Priority Date
WO-2015196118-A1	Alternative nucleic acid molecules and uses thereof	20140619
WO-2015196128-A2	Alternative nucleic acid molecules and uses thereof	20140619
WO-2015196130-A2	Alternative nucleic acid molecules and uses thereof	20140619
US-2015353930-A1	Methods of treating a metabolic syndrome by modulating heat shock protein (hsp) 90-beta	20140606
WO-2015188198-A2	Methods of treating a metabolic syndrome by modulating heat shock protein (hsp) 90-beta	20140606

PMID	Publication Date	Title	Journal
22248391	20120223	Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells	Journal of medicinal chemistry
21861932	20110824	Purine Nucleoside Phosphorylase mediated molecular chemotherapy and conventional chemotherapy: a tangible union against chemoresistant cancer	BMC cancer
21394111	20110601	Effect of expression of adenine phosphoribosyltransferase on the in vivo anti-tumor activity of prodrugs activated by E. coli purine nucleoside phosphorylase	Cancer gene therapy
19958550	20091203	Characterization of an engineered human purine nucleoside phosphorylase fused to an anti-her2/neu single chain Fv for use in ADEPT	Journal of experimental & clinical cancer research : CR
19640846	20091002	Structural basis for enzymatic evolution from a dedicated ADP-ribosyl cyclase to a multifunctional NAD hydrolase	The Journal of biological chemistry

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Amines and Anilines

[556-90-1]
Pseudothiohydantoin
[1158353-54-8]
(4-Pyrazol-1-ylphenyl)methanamine sulfuric acid
[932890-93-2]
1-{4-[(2,4-Dichlorobenzyl)oxy]-3-ethoxyphenyl}methanamine
[17583-40-3]
2-(Methylamino)benzonitrile
[856848-33-4]
2-Amino-4,5-dibromopyridine
[1823917-84-5]
2-Ethyl-4-(methylsulfonyl)aniline

Fluorinated Building Blocks

[1427357-61-6]
6-Fluoro-[1,2,4]triazolo[1,5-a]pyridine
[1946823-77-3]
[1,4-Dimethyl-3-(trifluoromethyl)-1H-pyrazol-5-yl]methanol
[2367-82-0]
1,2,3,5-Tetrafluorobenzene
[479552-94-8]
1H-Pyrrolo[2,3-b]pyridin-4-yl trifluoromethanesulfonate
[151585-93-2]
2-Amino-6-fluorobenzaldehyde
[459836-92-1]
3,6-Difluoro-2-methylbenzoic acid

Other Pyrimidines

[479552-94-8]
1H-Pyrrolo[2,3-b]pyridin-4-yl trifluoromethanesulfonate
[452-76-6]
2,4-Difluorotoluene
[2696462-69-6]
4-(4-Aminopyrimidin-2-yl)-2-methyl-1-(2-trimethylsilylethoxymethyl)pyrazol-3-one
[832739-73-8]
4-(3,5-Dichlorophenyl)pyrimidine-2-thiol
[1632145-37-9]
3-Methyl-3-(perfluoropyridin-4-yl)-1,5-dioxaspiro[5.5]undecane-2,4-dione
[451-46-7]
Ethyl 4-fluorobenzoate

Purines

[177966-67-5]
N6-Isopentenyladenine hydrochloride
[148238-36-2]
9-(prop-2-yn-1-yl)-9H-purin-6-amine
[1681-15-8]
2-Chloro-9H-purine
[853029-57-9]
8-bromo-7-(but-2-yn-1-yl)-3-methyl-1-((4-methylquinazolin-2-yl)methyl)-3,7-dihydro-1H-purine-2,6-dione
[19530-88-2]
2-amino-7-ethyl-3H-purin-6-one
[2922-28-3]
Adenine monohydrochloride

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Complexity:	154
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	153.04507331
Formal Charge:	0
Heavy Atom Count:	11
Hydrogen Bond Acceptor Count:	5
Hydrogen Bond Donor Count:	2
Isotope Atom Count:	0
Monoisotopic Mass:	153.04507331
Rotatable Bond Count:	0
Topological Polar Surface Area:	80.5 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	-0.1