2-Fluoro-6-hydroxyphenylboronic Acid - CAS 1256345-60-4
Catalog: |
BB006150 |
Product Name: |
2-Fluoro-6-hydroxyphenylboronic Acid |
CAS: |
1256345-60-4 |
Synonyms: |
(2-fluoro-6-hydroxyphenyl)boronic acid; (2-fluoro-6-hydroxyphenyl)boronic acid |
IUPAC Name: | (2-fluoro-6-hydroxyphenyl)boronic acid |
Description: | 2-Fluoro-6-hydroxyphenylboronic Acid (CAS# 1256345-60-4) is a synthetic reagent used in the preparation of alkylene-bridged [(3,4-dihydro-2H-benzo[b][1,4]oxazinyl) or (piperidinyl)(biphenyl-3-yl)pyrazolo[1,5-a]pyrimidinyl](tert-butoxy)acetic acid derivatives as HIV integrase inhibitors for treating HIV infection. |
Molecular Weight: | 155.92 |
Molecular Formula: | C6H6FO3B |
Canonical SMILES: | B(C1=C(C=CC=C1F)O)(O)O |
InChI: | InChI=1S/C6H6BFO3/c8-4-2-1-3-5(9)6(4)7(10)11/h1-3,9-11H |
InChI Key: | FPXQHZPCFRQWCP-UHFFFAOYSA-N |
Appearance: | Solid |
LogP: | -0.78890 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113248521-A | K-RAS G12C inhibitor and preparation method and application thereof | 20200211 |
CN-112159405-A | Pyridopyrimidinone compounds and application thereof | 20200204 |
CN-112159405-B | Pyridopyrimidinone compounds and application thereof | 20200204 |
WO-2021155716-A1 | Pyridopyrimidinone compound and application thereof | 20200204 |
US-2021230162-A1 | Spiro compounds as inhibitors of kras | 20200120 |
Complexity: | 133 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 156.0394024 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 3 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 156.0394024 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 60.7 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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