2-Ethoxybenzamidine Hydrochloride - CAS 18637-00-8

Name: 2-Ethoxybenzamidine Hydrochloride
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB014301
Product Name:	2-Ethoxybenzamidine Hydrochloride
CAS:	18637-00-8
Synonyms:	2-ethoxybenzenecarboximidamide;hydrochloride; 2-ethoxybenzenecarboximidamide;hydrochloride

Technical Data

IUPAC Name:	2-ethoxybenzenecarboximidamide;hydrochloride
Description:	An impurity of Vardenafil. Vardenafil is a PDE5 inhibitor used for the treatment of erectile dysfunction.
Molecular Weight:	200.67
Molecular Formula:	C9H13ClN2O
Canonical SMILES:	CCOC1=CC=CC=C1C(=N)N.Cl
InChI:	InChI=1S/C9H12N2O.ClH/c1-2-12-8-6-4-3-5-7(8)9(10)11;/h3-6H,2H2,1H3,(H3,10,11);1H
InChI Key:	NGMHLSBQVIXGNZ-UHFFFAOYSA-N
Boiling Point:	192 °C at 760 mmHg
Melting Point:	132-137 °C (dec.)
Density:	2.209 g/cm³
Appearance:	White to off-white solid
LogP:	2.97140

GHS Hazard Statement:	H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]
Precautionary Statement:	P264, P270, P273, P301+P312, P330, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
CN-103086920-A	Novel synthetic method of o-ethoxyl benzamidine hydrochloride	20111104
JP-2012511517-A	Compound having phenylpyrimidone skeleton, pharmaceutical composition thereof, production method thereof and use thereof	20081210
JP-5479488-B2	Compound having phenylpyrimidone skeleton, pharmaceutical composition thereof, production method thereof and use thereof	20081210
EP-2228370-A1	N-{1-Ã½3-(2-ethoxy-5-(4-ethylpiperazinyl)benzenesulfonyl)-4,5-dihydro-5-oxo-1,2,4-triazin-6-ylÂ¨ethyl}butyramide, the preparation method and use thereof	20071228
EP-2228370-B1	N-{1-[3-(2-ethoxy-5-(4-ethylpiperazinyl)benzenesulfonyl)-4,5-dihydro-5-oxo-1,2,4-triazin-6-yl]ethyl}butyramide, the preparation method and use thereof	20071228

Complexity:	159
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	2
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	200.0716407
Formal Charge:	0
Heavy Atom Count:	13
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	3
Isotope Atom Count:	0
Monoisotopic Mass:	200.0716407
Rotatable Bond Count:	3
Topological Polar Surface Area:	59.1 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0