2-Deoxy-L-ribose - CAS 18546-37-7
Catalog: |
BB014230 |
Product Name: |
2-Deoxy-L-ribose |
CAS: |
18546-37-7 |
Synonyms: |
2-Deoxy-L-erythro-pentose; L-2-Deoxyribose; L-erythro-Pentose, 2-deoxy-; L-threo-2-deoxy-pentose; L-Deoxyribose |
Application: |
2-Deoxy-L-ribose is an isomer of 2-Deoxy-D-ribose which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. |
IUPAC Name: | (3R,4S)-3,4,5-trihydroxypentanal |
Description: | 2-Deoxy-L-ribose (CAS# 18546-37-7) is an isomer of 2-Deoxy-D-ribose (D252000) which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione. |
Molecular Weight: | 134.13 |
Molecular Formula: | C5H10O4 |
Canonical SMILES: | C(C=O)C(C(CO)O)O |
InChI: | InChI=1S/C5H10O4/c6-2-1-4(8)5(9)3-7/h2,4-5,7-9H,1,3H2/t4-,5+/m1/s1 |
InChI Key: | ASJSAQIRZKANQN-UHNVWZDZSA-N |
Boiling Point: | 379.7±42.0°C at 760 mmHg |
Melting Point: | 74-77°C |
Purity: | ≥98% by GC |
Density: | 1.3±0.1 g/cm3 |
Solubility: | Soluble in Methanol (Slightly), Water (Slightly) |
Appearance: | Light Yellow to Pale Beige Solid |
Storage: | Store at -20°C |
MDL: | MFCD00132941 |
LogP: | -1.55310 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113151160-A | Method for improving cattle in-vitro fertilization efficiency and used freezing medium and thawing medium | 20210507 |
CN-111892047-A | Vanadium nitride hybrid and nitrogen-doped porous carbon material and preparation method and application thereof | 20200525 |
EP-3892731-A1 | Enzymatic method for preparation of cmp-neu5ac | 20200408 |
WO-2021204898-A1 | Enzymatic method for preparation of cmp-neu5ac | 20200408 |
JP-2021155376-A | Agents for collagen-related treatments | 20200327 |
PMID | Publication Date | Title | Journal |
20734229 | 20101101 | 2-deoxyribose deprives cultured astrocytes of their glutathione | Neurochemical research |
20544542 | 20100601 | Increased migration by stimulation of thymidine phosphorylase in endothelial cells of different origin | Nucleosides, nucleotides & nucleic acids |
20499682 | 20100101 | [Influence of the thymidine phosphorylase (platelet-derived endothelial cell growth factor) on tumor angiogenesis. Catalytic activity of enzyme inhibitors] | Postepy biochemii |
19199868 | 20090201 | 2-Deoxy-D-ribose, a downstream mediator of thymidine phosphorylase, regulates tumor angiogenesis and progression | Anti-cancer agents in medicinal chemistry |
18600526 | 20080601 | The role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in tumor behavior | Nucleosides, nucleotides & nucleic acids |
Complexity: | 83 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 2 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 134.05790880 |
Formal Charge: | 0 |
Heavy Atom Count: | 9 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 3 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 134.05790880 |
Rotatable Bond Count: | 4 |
Topological Polar Surface Area: | 77.8 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -2.3 |
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