2-Deoxy-L-ribose - CAS 18546-37-7

Name: 2-Deoxy-L-ribose
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB014230
Product Name:	2-Deoxy-L-ribose
CAS:	18546-37-7
Synonyms:	2-Deoxy-L-erythro-pentose; L-2-Deoxyribose; L-erythro-Pentose, 2-deoxy-; L-threo-2-deoxy-pentose; L-Deoxyribose
Application:	2-Deoxy-L-ribose is an isomer of 2-Deoxy-D-ribose which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.

Technical Data

IUPAC Name:	(3R,4S)-3,4,5-trihydroxypentanal
Description:	2-Deoxy-L-ribose is an isomer of 2-Deoxy-D-ribose which induces apoptosis by inhibiting the synthesis and increasing the efflux of glutathione.
Molecular Weight:	134.13
Molecular Formula:	C5H10O4
Canonical SMILES:	C(C=O)C(C(CO)O)O
InChI:	InChI=1S/C5H10O4/c6-2-1-4(8)5(9)3-7/h2,4-5,7-9H,1,3H2/t4-,5+/m1/s1
InChI Key:	ASJSAQIRZKANQN-UHNVWZDZSA-N
Boiling Point:	379.7±42.0°C at 760 mmHg
Melting Point:	74-77°C
Purity:	≥98% by GC
Density:	1.3±0.1 g/cm3
Solubility:	Soluble in Methanol (Slightly), Water (Slightly)
Appearance:	Light Yellow to Pale Beige Solid
Storage:	Store at -20°C
MDL:	MFCD00132941
LogP:	-1.55310

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

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PMID	Publication Date	Title	Journal
20734229	20101101	2-deoxyribose deprives cultured astrocytes of their glutathione	Neurochemical research
20544542	20100601	Increased migration by stimulation of thymidine phosphorylase in endothelial cells of different origin	Nucleosides, nucleotides & nucleic acids
20499682	20100101	[Influence of the thymidine phosphorylase (platelet-derived endothelial cell growth factor) on tumor angiogenesis. Catalytic activity of enzyme inhibitors]	Postepy biochemii
19199868	20090201	2-Deoxy-D-ribose, a downstream mediator of thymidine phosphorylase, regulates tumor angiogenesis and progression	Anti-cancer agents in medicinal chemistry
18600526	20080601	The role of platelet-derived endothelial cell growth factor/thymidine phosphorylase in tumor behavior	Nucleosides, nucleotides & nucleic acids

Complexity:	83
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	2
Defined Bond Stereocenter Count:	0
Exact Mass:	134.05790880
Formal Charge:	0
Heavy Atom Count:	9
Hydrogen Bond Acceptor Count:	4
Hydrogen Bond Donor Count:	3
Isotope Atom Count:	0
Monoisotopic Mass:	134.05790880
Rotatable Bond Count:	4
Topological Polar Surface Area:	77.8 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	-2.3