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| IUPAC Name: | 3-bis[di(propan-2-yl)amino]phosphanyloxypropanenitrile |
| Description: | 2-Cyanoethyl N,N,N',N'-tetraisopropylphosphorodiamidite is a chemical compound used in the synthesis of oligonucleotides. It serves as a phosphoramidite building block, facilitating the addition of nucleotide units during solid-phase oligonucleotide synthesis. The cyanoethyl group protects the phosphorus atom, while the tetraisopropylphosphorodiamidite moiety enables efficient coupling reactions with nucleotides. This reagent plays a crucial role in the automated synthesis of oligonucleotides, allowing for the controlled assembly of DNA or RNA sequences with high purity and yield. |
| Molecular Weight: | 301.41 |
| Molecular Formula: | C15H32N3OP |
| Canonical SMILES: | CC(C)N(C(C)C)P(N(C(C)C)C(C)C)OCCC#N |
| InChI: | InChI=1S/C15H32N3OP/c1-12(2)17(13(3)4)20(19-11-9-10-16)18(14(5)6)15(7)8/h12-15H,9,11H2,1-8H3 |
| InChI Key: | RKVHNYJPIXOHRW-UHFFFAOYSA-N |
| Boiling Point: | 298.1±0.0°C at 760 mmHg |
| Purity: | ≥95% |
| Density: | 0.949 g/mL at 25°C |
| Solubility: | Soluble in Acetonitrile (Slightly), Benzene, Chloroform (Slightly), Methanol (Slightly) |
| Appearance: | Clear Light Yellow Oily Matter |
| Storage: | Store at 2-8°C under inert atmosphere |
| MDL: | MFCD00012213 |
| LogP: | 4.38118 |
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Phosphorus Compounds
3-(Trihydroxysilyl)propyl methylphosphonate, monosodium salt solution
Dichloro[(R)-(+)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl]palladium(II)
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