2-Chloroquinoxaline - CAS 1448-87-9
Catalog: |
BB009848 |
Product Name: |
2-Chloroquinoxaline |
CAS: |
1448-87-9 |
Synonyms: |
2-chloroquinoxaline |
IUPAC Name: | 2-chloroquinoxaline |
Description: | 2-Chloroquinoxaline (CAS# 1448-87-9) is used as a reagent to synthesize Chloroquinoxaline sulfamide, a compound that is active against human cancers. 2-Chloroquinoxaline is also used as a starting material to synthesize a variety of novel arylaminoquinoxalines, a group of compounds that exhibit antimalarial activity in rats. |
Molecular Weight: | 164.59 |
Molecular Formula: | C8H5ClN2 |
Canonical SMILES: | C1=CC=C2C(=C1)N=CC(=N2)Cl |
InChI: | InChI=1S/C8H5ClN2/c9-8-5-10-6-3-1-2-4-7(6)11-8/h1-5H |
InChI Key: | BYHVGQHIAFURIL-UHFFFAOYSA-N |
Boiling Point: | 100 °C (1.4 mmHg) |
Density: | 1.349 g/cm3 |
Appearance: | White to gray purple to tan powder |
MDL: | MFCD00043907 |
LogP: | 2.28320 |
GHS Hazard Statement: | H301 (92.86%): Toxic if swallowed [Danger Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-213348898-U | Chloride condensation equipment | 20200927 |
CN-112028840-A | Synthetic method of 4-position quinoxalinyl substituted alcohol derivative | 20200907 |
CN-112028840-B | Synthetic method of 4-position quinoxalinyl substituted alcohol derivative | 20200907 |
KR-102178181-B1 | Novel hydrazone derivatives comprising aryl or heteroaryl group substituted at terminal amine and use thereof | 20200331 |
KR-20200076655-A | Novel hydrazone derivatives comprising aryl or heteroaryl group substituted at terminal amine and use thereof | 20200331 |
PMID | Publication Date | Title | Journal |
21588753 | 20100828 | 2-(3-Nitro-phen-oxy)quinoxaline | Acta crystallographica. Section E, Structure reports online |
21582465 | 20090311 | 1-Naphthyl quinoxalin-2-yl ether | Acta crystallographica. Section E, Structure reports online |
21582466 | 20090311 | 2-Naphthyl quinoxalin-2-yl ether | Acta crystallographica. Section E, Structure reports online |
21582127 | 20090204 | 2-Chloro-quinoxaline | Acta crystallographica. Section E, Structure reports online |
21201795 | 20080823 | Phenyl quinoxalin-2-yl ether | Acta crystallographica. Section E, Structure reports online |
Complexity: | 140 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 164.0141259 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 164.0141259 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 25.8 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.2 |
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