2-Chlorophenyl phosphorodichloridate - CAS 15074-54-1
Catalog: |
BB010568 |
Product Name: |
2-Chlorophenyl phosphorodichloridate |
CAS: |
15074-54-1 |
Synonyms: |
1-chloro-2-dichlorophosphoryloxybenzene |
IUPAC Name: | 1-chloro-2-dichlorophosphoryloxybenzene |
Description: | 2-Chlorophenyl Phosphorodichloridate was used to synthesize asymmetric cyclopropyl carbocyclic nucleosides. |
Molecular Weight: | 245.43 |
Molecular Formula: | C6H4Cl3O2P |
Canonical SMILES: | C1=CC=C(C(=C1)OP(=O)(Cl)Cl)Cl |
InChI: | InChI=1S/C6H4Cl3O2P/c7-5-3-1-2-4-6(5)11-12(8,9)10/h1-4H |
InChI Key: | VLDPXPPHXDGHEW-UHFFFAOYSA-N |
Boiling Point: | 135-137 °C12 mmHg (lit.) |
Purity: | > 97.0 % (T) |
Density: | 1.491 g/mL at 25 °C (lit.) |
Appearance: | Colorless liquid |
Storage: | 2-8 °C |
MDL: | MFCD00009704 |
LogP: | 4.30450 |
GHS Hazard Statement: | H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] |
Precautionary Statement: | P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2021167882-A1 | Antiviral compounds | 20200218 |
US-2021129179-A1 | Surface modification in the vapor phase | 20191011 |
WO-2021020879-A1 | Dinucleotide compounds for treating cancers and medical uses thereof | 20190730 |
WO-2020214565-A1 | Calibration methods and compositions for biomolecule analysis | 20190415 |
CN-111051325-A | Spirothiacyclobutanenucleosides | 20170901 |
PMID | Publication Date | Title | Journal |
22273279 | 20120316 | 2'-Azido RNA, a versatile tool for chemical biology: synthesis, X-ray structure, siRNA applications, click labeling | ACS chemical biology |
21171007 | 20110103 | Chemical synthesis of site-specifically 2'-azido-modified RNA and potential applications for bioconjugation and RNA interference | Chembiochem : a European journal of chemical biology |
Complexity: | 193 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 243.901449 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 243.901449 |
Rotatable Bond Count: | 2 |
Topological Polar Surface Area: | 26.3 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.6 |
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