2-Chloro-8-methylquinoline-3-carboxaldehyde - CAS 73568-26-0

Name: 2-Chloro-8-methylquinoline-3-carboxaldehyde
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB034867
Product Name:	2-Chloro-8-methylquinoline-3-carboxaldehyde
CAS:	73568-26-0
Synonyms:	2-chloro-8-methylquinoline-3-carbaldehyde

Technical Data

IUPAC Name:	2-chloro-8-methylquinoline-3-carbaldehyde
Description:	2-Chloro-8-methylquinoline-3-carboxaldehyde acts as a reagent in the synthesis of 2-Azetidinones from 2-chloro-8-Me-3-quinolinecarbaldehyde as potential antimicrobial agents, preparation and antibacterial activity of thiazoloquinoline Schiff bases as potential antibacterial agents.
Molecular Weight:	205.64
Molecular Formula:	C11H8ClNO
Canonical SMILES:	CC1=CC=CC2=CC(=C(N=C12)Cl)C=O
InChI:	InChI=1S/C11H8ClNO/c1-7-3-2-4-8-5-9(6-14)11(12)13-10(7)8/h2-6H,1H3
InChI Key:	YPBRSXNRWFUUOE-UHFFFAOYSA-N
Boiling Point:	350.8 °C at 760 mmHg
Density:	1.312 g/cm³
MDL:	MFCD02227041
LogP:	3.00910

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
WO-2020241853-A1	Benzotriazole derivative	20190531
US-2016222012-A1	Heterocyclic compounds as inhibitors of class I PI3KS	20150129
US-9637488-B2	Heterocyclic compounds as inhibitors of class I PI3KS	20150129
WO-2017132157-A1	Heterocyclic compounds as inhibitors of class i pi3ks	20150129
WO-2014106800-A2	Substituted 2-amino pyrimidine derivatives as kinase inhibitors	20130104

PMID	Publication Date	Title	Journal
21589427	20101110	N,N'-Bis[(E)-(2-chloro-8-methyl-quinolin-3-yl)methyl-idene]ethane-1,2-diamine	Acta crystallographica. Section E, Structure reports online
21589041	20101020	N-[(2-Chloro-8-methyl-quinolin-3-yl)meth-yl]-4-meth-oxy-aniline	Acta crystallographica. Section E, Structure reports online
21578319	20091013	2-Chloro-8-methyl-quinoline-3-carbaldehyde	Acta crystallographica. Section E, Structure reports online

Complexity:	221
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	205.0294416
Formal Charge:	0
Heavy Atom Count:	14
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	205.0294416
Rotatable Bond Count:	1
Topological Polar Surface Area:	30 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	3