2-Chloro-6-methoxypyridine - CAS 17228-64-7

Name: 2-Chloro-6-methoxypyridine
Brand: BOC Sciences
Rating: 5 (1 reviews)

Technical Data

IUPAC Name:	2-chloro-6-methoxypyridine
Description:	2-Chloro-6-methoxypyridine (CAS# 17228-64-7) is a reagent used to synthesize imidazo[1,2-a]pyrimidines as functionally selective GABAA ligands. It can also be used to synthesize oxazolidinedione-arylpyridinones as EP3 receptor antagonists.
Molecular Weight:	143.57
Molecular Formula:	C6H6ClNO
Canonical SMILES:	COC1=NC(=CC=C1)Cl
InChI:	InChI=1S/C6H6ClNO/c1-9-6-4-2-3-5(7)8-6/h2-4H,1H3
InChI Key:	VAVGOGHLNAJECD-UHFFFAOYSA-N
Boiling Point:	185-186 °C
Density:	1.207 g/cm³
Appearance:	Colorless to light yellow clear liquid
MDL:	MFCD00006265
LogP:	1.74360

GHS Hazard Statement:	H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]
Precautionary Statement:	P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501
Signal Word:	Warning

Publication Number	Title	Priority Date
CN-111087343-A	Hydroxypyridine ligand, preparation method and catalytic application thereof	20191129
WO-2021011913-A1	Tau-protein targeting compounds and associated methods of use	20190717
CN-111151248-A	Method for catalyzing heterocyclic halogen-containing organic matter hydrogenation dehalogenation by using supported metal oxide	20190619
WO-2020236692-A1	Pyridinone derivatives as selective cytotoxic agents against hiv infected cells	20190522
JP-2020152649-A	Method for producing heterocyclic compound	20190318

Complexity:	89.1
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	143.0137915
Formal Charge:	0
Heavy Atom Count:	9
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	143.0137915
Rotatable Bond Count:	1
Topological Polar Surface Area:	22.1 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	3