2-Chloro-5-iodo-3-nitropyridine - CAS 426463-05-0
Catalog: |
BB025188 |
Product Name: |
2-Chloro-5-iodo-3-nitropyridine |
CAS: |
426463-05-0 |
Synonyms: |
Pyridine, 2-chloro-5-iodo-3-nitro- |
IUPAC Name: | 2-chloro-5-iodo-3-nitropyridine |
Description: | 2-Chloro-5-iodo-3-nitropyridine (CAS# 426463-05-0) is used in preparation of nitrogen heterocycles as colony stimulating factor-1 receptor (CSF-1R) inhibitors. |
Molecular Weight: | 284.44 |
Molecular Formula: | C5H2ClIN2O2 |
Canonical SMILES: | C1=C(C(=NC=C1I)Cl)[N+](=O)[O-] |
InChI: | InChI=1S/C5H2ClIN2O2/c6-5-4(9(10)11)1-3(7)2-8-5/h1-2H |
InChI Key: | PIJMRJPJERUFNI-UHFFFAOYSA-N |
Boiling Point: | 334.0±37.0°C at 760 mmHg |
Melting Point: | 77-79°C |
Purity: | ≥95% |
Density: | 2.213±0.06 g/cm3 |
Appearance: | Solid |
Storage: | Store at 2-8°C under inert gas (nitrogen or Argon) |
MDL: | MFCD04038568 |
LogP: | 2.77100 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H318 (100%): Causes serious eye damage [Danger Serious eye damage/eye irritation]; H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
Precautionary Statement: | P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P354+P338, P317, P319, P321, P330, P332+P317, P362+P364, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
AU-2016297558-A1 | Colony stimulating factor-1 receptor (CSF-1R) inhibitors | 20150720 |
CA-2993018-A1 | Colony stimulating factor-1 receptor (csf-1r) inhibitors | 20150720 |
EP-3325471-A1 | Colony stimulating factor-1 receptor (csf-1r) inhibitors | 20150720 |
JP-2018524381-A | Colony stimulating factor-1 receptor (CSF-1R) inhibitor | 20150720 |
KR-20180030199-A | Colony stimulating factor-1 receptor (CSF-1R) inhibitor | 20150720 |
Complexity: | 163 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 283.88495 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 283.88495 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 58.7 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.3 |
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