2-Chloro-4-methylquinoline - CAS 634-47-9
Catalog: |
BB032154 |
Product Name: |
2-Chloro-4-methylquinoline |
CAS: |
634-47-9 |
Synonyms: |
2-chloro-4-methylquinoline |
IUPAC Name: | 2-chloro-4-methylquinoline |
Description: | 2-Chloro-4-methylquinoline (CAS# 634-47-9) is a useful synthetic intermediate. It is an intermediate used to synthesize 4-Methyl-2-(1-piperidinyl)-quinoline (M320715) which is a potent inhibitor of TRPC4 channels, responsible for various stimulation, muscle response due to interaction with the environment. 2-Chloro-4-methyl-quinoline is also considered as a cyanine dye. |
Molecular Weight: | 177.63 |
Molecular Formula: | C10H8ClN |
Canonical SMILES: | CC1=CC(=NC2=CC=CC=C12)Cl |
InChI: | InChI=1S/C10H8ClN/c1-7-6-10(11)12-9-5-3-2-4-8(7)9/h2-6H,1H3 |
InChI Key: | PFEIMKNQOIFKSW-UHFFFAOYSA-N |
Boiling Point: | 296 °C |
Melting Point: | 55-58 °C |
Purity: | 95 % |
Density: | 1.225 g/cm3 |
Appearance: | White to light yellow crystal powder |
MDL: | MFCD00006742 |
LogP: | 3.19660 |
GHS Hazard Statement: | H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation] |
Precautionary Statement: | P261, P264, P271, P280, P302+P352, P304+P340, P305+P351+P338, P312, P321, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-111533689-A | 2, 2' -biquinoline compound and one-pot preparation method thereof | 20200528 |
WO-2021113698-A1 | Masp-2 inhibitors and methods of use | 20191204 |
CN-110669546-A | Catalytic slurry oil filtering device and method suitable for long-period operation | 20191031 |
CN-211111877-U | Catalytic slurry oil filtering device suitable for long-period operation | 20191031 |
CN-109734705-B | Method for preparing N-heterocyclic aromatic hydrocarbon derivative through dehalogenation alkylation | 20190201 |
PMID | Publication Date | Title | Journal |
21587537 | 20100911 | N-[(2-Chloro-3-quinol-yl)meth-yl]-4-fluoro-aniline | Acta crystallographica. Section E, Structure reports online |
Complexity: | 160 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 177.0345270 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 0 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 177.0345270 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 12.9 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 3.5 |
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