2-C-Methyl-D-ribonic Acid gamma-Lactone - CAS 492-30-8

Name: 2-C-Methyl-D-ribonic Acid gamma-Lactone
Brand: BOC Sciences
Rating: 5 (1 reviews)

Catalog:	BB026666
Product Name:	2-C-Methyl-D-ribonic Acid gamma-Lactone
CAS:	492-30-8
Synonyms:	2-C-Methyl-D-ribono-1,4-lactone; 2-C-Methyl-D-ribonic Acid γ-Lactone; 2-C-Methyl-D-ribo-pentonic Acid γ-Lactone; NSC 19768; NSC 62382; α-D-Glucosaccharinic Acid γ-Lactone; 2,3-O-Isopropylidene-2-C-methyl-D-ribono-1,4-lactone

Technical Data

IUPAC Name:	(3R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)-3-methyloxolan-2-one
Description:	Used in synthesis of enantiomerically pure 4-substituted riboses; also for preparing saccharinic acids and lactones via Amadori rearrangement for use as synthons toward herbicidal esters and branched nucleosides.
Molecular Weight:	162.14
Molecular Formula:	C6H10O5
Canonical SMILES:	CC1(C(C(OC1=O)CO)O)O
InChI:	InChI=1S/C6H10O5/c1-6(10)4(8)3(2-7)11-5(6)9/h3-4,7-8,10H,2H2,1H3/t3-,4-,6-/m1/s1
InChI Key:	WJBVKNHJSHYNHO-ZMIZWQJLSA-N
Boiling Point:	338.3±11.0°C (Predicted)
Melting Point:	150-160°C
Purity:	≥95%
Density:	1.512±0.06 g/cm3 (Predicted)
Solubility:	Soluble in DMSO (Slightly), Methanol (Slightly), Water (Slightly)
Appearance:	White to Off-white Solid
Storage:	Store at -20°C
LogP:	-1.98400

Publication Number	Title	Priority Date
WO-2020210938-A1	Quinazoline derivatives as cd73 inhibitors	20190415
WO-2020211668-A1	Cd73 inhibitors	20190415
TW-202104195-A	Cd73 inhibitors	20190415
CN-108440613-B	Synthesis process of (2'R) -2' -deoxy-2 '-fluoro-2' -methyluridine	20180326
WO-2019041317-A1	Method for preparing sofbreve lactone intermediate	20170828

Complexity:	180
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	3
Defined Bond Stereocenter Count:	0
Exact Mass:	162.05282342
Formal Charge:	0
Heavy Atom Count:	11
Hydrogen Bond Acceptor Count:	5
Hydrogen Bond Donor Count:	3
Isotope Atom Count:	0
Monoisotopic Mass:	162.05282342
Rotatable Bond Count:	1
Topological Polar Surface Area:	87
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	-1.2