2-Bromo-4'-fluoroacetophenone - CAS 403-29-2

Catalog:	BB024454
Product Name:	2-Bromo-4'-fluoroacetophenone
CAS:	403-29-2
Synonyms:	2-bromo-1-(4-fluorophenyl)ethanone

Technical Data

Safety and Hazards

Patents

Literatures

Computed Properties

IUPAC Name:	2-bromo-1-(4-fluorophenyl)ethanone
Description:	2-Bromo-4'-fluoroacetophenone (CAS# 403-29-2) is an intermediate in the synthetic preparation of competitive inhibitors of aromatase.
Molecular Weight:	217.04
Molecular Formula:	C8H6BrFO
Canonical SMILES:	C1=CC(=CC=C1C(=O)CBr)F
InChI:	InChI=1S/C8H6BrFO/c9-5-8(11)6-1-3-7(10)4-2-6/h1-4H,5H2
InChI Key:	ZJFWCELATJMDNO-UHFFFAOYSA-N
Boiling Point:	150 °C (12 mmHg)
Melting Point:	46-49 °C
Purity:	95 %
Density:	1.568 g/cm³
Appearance:	Beige to light grey-green cryst. powder or flakes
Storage:	Keep Cold
LogP:	2.40330

Publication Number	Title	Priority Date
CN-112694472-A	BuChE-IDO1 inhibitor, preparation method and application thereof	20201225
CN-111423432-A	(S) -4/5-phenyl-2- (pyrrolidine-2-yl) thiazole TRPV1 antagonist and preparation and application thereof	20200511
WO-2021190615-A1	Compounds as casein kinase inhibitors	20200327
WO-2021190616-A1	Methods for inhibiting casein kinases	20200327
US-2021251982-A1	Methods for treating neurological symptoms associated with lysosomal storage diseases	20200203

PMID	Publication Date	Title	Journal
22524250	20120510	Imidazolopiperazines: lead optimization of the second-generation antimalarial agents	Journal of medicinal chemistry
22347113	20120201	2-(4-Fluoro-phen-yl)-2-oxoethyl 2-methoxy-benzoate	Acta crystallographica. Section E, Structure reports online
22199934	20111201	2-(4-Fluoro-phen-yl)-2-oxoethyl 4-meth-oxy-benzoate	Acta crystallographica. Section E, Structure reports online
22219880	20111101	2-(4-Fluoro-phen-yl)-2-oxoethyl 3-(trifluoro-meth-yl)benzoate	Acta crystallographica. Section E, Structure reports online
21202170	20080402	Di-μ-iodido-bis-{[(4-fluoro-benzoyl-methyl-ene)triphenyl-λ-phospho-rane]iodido-mercury(II)}	Acta crystallographica. Section E, Structure reports online

Related Products

Online Inquiry

Name:

* Phone:

* Service & Products of Interested:

Project Description:

* Quantity:

* Email:

* Verification Code:

Customer Support

If the product you need is not in our catalog, please contact us in time to submit your needs. You can help our website get better and better. Why not submit the request today?

Submit Requirement

Customer Centered

Global Delivery

Warehouses in multiple cities to ensure fast delivery

Quality Assurance

Strict process parameter control to ensure product quality

Large Stock

> 20,000 building blocks and intermediates from stock

Process Scale-up

Process scale-up from lab to industrial scale

Flexible Batch Size

Flexible batch size for diverse industrial demands

Related Functional Groups

Carbonyl Compounds

[91125-43-8]
Sulfophenyl nonanoate sodium salt
[89908-23-6]
2-Propenoic acid, 2-(3',3'-dimethyl-6-nitrospiro[2H-1-benzopyran-2,2'-[2H]indol]-1'(3'H)-yl)ethyl ester
[1383427-98-2]
(S)-Hexahydropyrazino[2,1-c][1,4]oxazin-4(3H)-one hydrochloride
[959574-98-2]
(3-Phenyl-1H-pyrazol-1-yl)acetic acid
[35153-16-3]
(Z)-10-Tetradecenyl Acetate
[956439-56-8]
1-(Carboxymethyl)-3-nitro-1H-pyrazole-5-carboxylic acid

Fluorinated Building Blocks

[2367-82-0]
1,2,3,5-Tetrafluorobenzene
[479552-94-8]
1H-Pyrrolo[2,3-b]pyridin-4-yl trifluoromethanesulfonate
[2454490-85-6]
2-(7,8-Difluoro-1-naphthyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
[1018125-51-3]
2-(6-Ethyl-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid
[452-76-6]
2,4-Difluorotoluene
[1170836-29-9]
3-(1',3'-Dimethyl-5-(trifluoromethyl)-1'H,2H-[3,4'-bipyrazol]-2-yl)propanenitrile

Halides

[1820736-42-2]
1-{4-[3-(Trifluoromethyl)-1H-pyrazol-1-yl]phenyl}methanamine hydrochloride
[1431970-24-9]
2,2-Difluoro-N-[1-(1-methylpyrazol-4-yl)ethyl]ethanamine hydrochloride
[1936054-65-7]
2,4-Dichloro-3,6-dimethylquinoline
[452-76-6]
2,4-Difluorotoluene
[267242-99-9]
2-Chloro-4-methyl-6,7-dihydro-5H-cyclopenta[b]pyridine
[832740-55-3]
3-[(4-Chloro-2-methylphenoxy)methyl]-4-methoxybenzaldehyde

Other Pyrimidines

[351-28-0]
3'-Fluoroacetanilide
[927800-47-3]
4-Chloro-6-fluoro-2-trichloromethyl-quinoline
[1160246-50-3]
2-((4-(P-Tolyl)-6-(trifluoromethyl)pyrimidin-2-yl)oxy)ethanamine
[860790-29-0]
N-[4-Cyclopropyl-6-(trifluoromethyl)pyrimidin-2-yl]propane-1,3-diamine
[77776-68-2]
2,4,8-Trichloropyrimido[5,4-d]pyrimidine
[672-45-7]
6-(Trifluoromethyl)uracil

GHS Hazard Statement:	H314 (91.49%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation]
Precautionary Statement:	P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501
Signal Word:	Danger

Complexity:	141
Compound Is Canonicalized:	Yes
Covalently-Bonded Unit Count:	1
Defined Atom Stereocenter Count:	0
Defined Bond Stereocenter Count:	0
Exact Mass:	215.95861
Formal Charge:	0
Heavy Atom Count:	11
Hydrogen Bond Acceptor Count:	2
Hydrogen Bond Donor Count:	0
Isotope Atom Count:	0
Monoisotopic Mass:	215.95861
Rotatable Bond Count:	2
Topological Polar Surface Area:	17.1 Å²
Undefined Atom Stereocenter Count:	0
Undefined Bond Stereocenter Count:	0
XLogP3:	2.5