2-Azetidinone - CAS 930-21-2
Catalog: |
BB040741 |
Product Name: |
2-Azetidinone |
CAS: |
930-21-2 |
Synonyms: |
azetidin-2-one |
IUPAC Name: | azetidin-2-one |
Description: | 2-Azetidinone are β-lactams which maintain potential for antibiotic activity. Potential to act as tubulin polymerization inhibitors. |
Molecular Weight: | 71.08 |
Molecular Formula: | C3H5NO |
Canonical SMILES: | C1CNC1=O |
InChI: | InChI=1S/C3H5NO/c5-3-1-2-4-3/h1-2H2,(H,4,5) |
InChI Key: | MNFORVFSTILPAW-UHFFFAOYSA-N |
Boiling Point: | 106 °C (15 mmHg) |
Melting Point: | 74-76 °C |
Purity: | 98 % |
Density: | 1.119 g/cm3 |
Appearance: | Colorless solid |
Storage: | 2-8 °C |
MDL: | MFCD00013328 |
LogP: | -0.16490 |
GHS Hazard Statement: | H314 (100%): Causes severe skin burns and eye damage [Danger Skin corrosion/irritation] |
Precautionary Statement: | P260, P264, P280, P301+P330+P331, P303+P361+P353, P304+P340, P305+P351+P338, P310, P321, P363, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2015188727-A1 | Method for preparing azetidinone compound and intermediate of azetidinone compound | 20140609 |
WO-2015184544-A1 | Use of anti-aging glycopeptides to enhance pancreatic cell health, survival and improve transplant outcome | 20140604 |
WO-2015158913-A1 | Novel antiviral and antitumoral compounds | 20140417 |
WO-2015148962-A1 | Compositions and methods for treating neurodegenerative diseases | 20140328 |
US-2015266867-A1 | Monobactam organic compounds for the treatment of bacterial infections | 20140324 |
PMID | Publication Date | Title | Journal |
33169987 | 20201221 | Cell Membrane Transporters Facilitate the Accumulation of Hepatocellular Flucloxacillin Protein Adducts: Implication in Flucloxacillin-Induced Liver Injury | Chemical research in toxicology |
32869927 | 20201201 | The molecular effect of 1,4,7-triazacyclononane on oxidative stress parameters in human hepatocellular carcinoma (HepG2) cells | Journal of biochemical and molecular toxicology |
32666660 | 20201101 | Ceftriaxone pretreatment confers neuroprotection in rats with acute glaucoma and reduces the score of seizures induced by pentylenotetrazole in mice | Journal of biochemical and molecular toxicology |
32255609 | 20200612 | In Vitro Characterization of ETX1317, a Broad-Spectrum β-Lactamase Inhibitor That Restores and Enhances β-Lactam Activity against Multi-Drug-Resistant Enterobacteriales, Including Carbapenem-Resistant Strains | ACS infectious diseases |
32173352 | 20200501 | Fetal alcohol spectrum disorders model alters the functionality of glutamatergic neurotransmission in adult zebrafish | Neurotoxicology |
Complexity: | 59.9 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 71.037113783 |
Formal Charge: | 0 |
Heavy Atom Count: | 5 |
Hydrogen Bond Acceptor Count: | 1 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 71.037113783 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 29.1 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | -0.8 |
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