2-Aminoquinoline - CAS 580-22-3
Catalog: |
BB029905 |
Product Name: |
2-Aminoquinoline |
CAS: |
580-22-3 |
Synonyms: |
quinolin-2-amine |
IUPAC Name: | quinolin-2-amine |
Description: | 2-Aminoquinoline (CAS# 580-22-3) is a useful research chemical. |
Molecular Weight: | 144.17 |
Molecular Formula: | C9H8N2 |
Canonical SMILES: | C1=CC=C2C(=C1)C=CC(=N2)N |
InChI: | InChI=1S/C9H8N2/c10-9-6-5-7-3-1-2-4-8(7)11-9/h1-6H,(H2,10,11) |
InChI Key: | GCMNJUJAKQGROZ-UHFFFAOYSA-N |
Boiling Point: | 304.9 °C at 760 mmHg |
Melting Point: | 125 °C |
Flash Point: | 163.6±7.6 °C |
Purity: | 98 % |
Density: | 1.21 g/cm3 |
Solubility: | In Vitro: DMSO: 100 mg/mL(693.63 mM;Need ultrasonic) |
Appearance: | Colorless to light yellow liquid |
Storage: | 4°C, protect from light * In solvent : -80°C, 6 months -20°C, 1 month (protect from light) |
MDL: | MFCD00038079 |
LogP: | 2.39820 |
Vapor Pressure: | 0.0±0.6 mmHg at 25°C |
GHS Hazard Statement: | H302 (95.24%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
WO-2021121146-A1 | Crystal form a of aminopyrimidine mesylate compound, preparation method therefor, and application thereof | 20191218 |
WO-2021127183-A1 | Polymeric surfactant compound | 20191218 |
WO-2021126977-A1 | Methods of treating iga nephropathy with atrasentan | 20191217 |
WO-2021127000-A1 | Myeloid cell-targeted nanoparticles and related compositions and methods | 20191217 |
WO-2021113917-A1 | Therapeutic compositions and methods for prevention and treatment of diastolic dysfunction | 20191211 |
PMID | Publication Date | Title | Journal |
23659857 | 20130615 | Synthesis and evaluation of phenoxyoxazaphospholidine, phenoxyoxazaphosphinane, and benzodioxaphosphininamine sulfides and related compounds as potential anti-malarial agents | Bioorganic & medicinal chemistry letters |
23433124 | 20130221 | Potent in vivo anti-malarial activity and representative snapshot pharmacokinetic evaluation of artemisinin-quinoline hybrids | Malaria journal |
22901673 | 20121001 | Synthesis and comparison of antiplasmodial activity of (+), (-) and racemic 7-chloro-4-(N-lupinyl)aminoquinoline | Bioorganic & medicinal chemistry |
22878685 | 20120901 | Lys05: a new lysosomal autophagy inhibitor | Autophagy |
22944678 | 20120801 | Aminoquinolines as fluorescent labels for hydrophilic interaction liquid chromatography of oligosaccharides | Biological chemistry |
Complexity: | 136 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 144.068748264 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 144.068748264 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 38.9 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.9 |
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