2-Amino-6,6-difluorospiro[3.3]heptane Hydrochloride - CAS 1423032-71-6
Catalog: |
BB009349 |
Product Name: |
2-Amino-6,6-difluorospiro[3.3]heptane Hydrochloride |
CAS: |
1423032-71-6 |
Synonyms: |
2,2-difluoro-6-spiro[3.3]heptanamine;hydrochloride; 2,2-difluorospiro[3.3]heptan-6-amine;hydrochloride |
IUPAC Name: | 2,2-difluorospiro[3.3]heptan-6-amine;hydrochloride |
Description: | 2-Amino-6,6-difluorospiro[3.3]heptane Hydrochloride (CAS# 1423032-71-6) is used as a reactant in the preparation of fluorinated building blocks based on spiroheptane scaffold by deoxofluorination of sterically hindered ketones using XtalFluor-M reagent. |
Molecular Weight: | 183.63 |
Molecular Formula: | C7H12ClF2N |
Canonical SMILES: | C1C(CC12CC(C2)(F)F)N.Cl |
InChI: | InChI=1S/C7H11F2N.ClH/c8-7(9)3-6(4-7)1-5(10)2-6;/h5H,1-4,10H2;1H |
InChI Key: | QXXFNNVWYZNJFY-UHFFFAOYSA-N |
LogP: | 3.02530 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
JP-2021119176-A | Cyclic peptide compound with Kras inhibitory effect | 20191107 |
JP-6880352-B1 | Cyclic peptide compound with Kras inhibitory effect | 20191107 |
KR-20210064234-A | Cyclic peptide compound having Kras inhibitory action | 20191107 |
WO-2021090855-A1 | Cyclic peptide compound having kras inhibiting action | 20191107 |
US-2019382373-A1 | 6-AMINOPYRIDIN-3-YL PYRAZOLES AS MODULATORS OF RORgT | 20180618 |
Complexity: | 151 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 2 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 183.0626334 |
Formal Charge: | 0 |
Heavy Atom Count: | 11 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 2 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 183.0626334 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 26 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
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Amines and Anilines
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