2-Amino-5-methylthiazole - CAS 7305-71-7
Catalog: |
BB034749 |
Product Name: |
2-Amino-5-methylthiazole |
CAS: |
7305-71-7 |
Synonyms: |
5-methyl-1,3-thiazol-2-amine |
IUPAC Name: | 5-methyl-1,3-thiazol-2-amine |
Description: | 2-Amino-5-methylthiazole is an aminothiazole derivative used in characterization and DNA-interaction studies via formation of metal complexes that bind competitively to DNA. 2-Amino-5-methylthiazole can be used in solar cells to influence the interaction. |
Molecular Weight: | 114.17 |
Molecular Formula: | C4H6N2S |
Canonical SMILES: | CC1=CN=C(S1)N |
InChI: | InChI=1S/C4H6N2S/c1-3-2-6-4(5)7-3/h2H,1H3,(H2,5,6) |
InChI Key: | GUABFMPMKJGSBQ-UHFFFAOYSA-N |
Boiling Point: | 232.5 °C at 760 mmHg |
Melting Point: | 93-95 °C |
Purity: | 99 % |
Density: | 1.258 g/cm3 |
Appearance: | Brown solid |
MDL: | MFCD00078317 |
LogP: | 1.61490 |
GHS Hazard Statement: | H302: Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P260, P264, P270, P273, P301+P312, P314, P330, P391, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-113200939-A | Bis (1, 3-thiazole) amine and preparation method thereof | 20210331 |
CN-113045993-A | Polishing solution for processing ultra-smooth low-damage bearing steel surface and application thereof | 20210325 |
CN-112979579-A | Low-temperature diazonium salt continuous preparation method of halogenated thiazole compound | 20210317 |
JP-2021006572-A | Aminonaphthoquinone compounds, and pharmaceutical compositions for blocking the ubiquitination-proteasome system in disease | 20201005 |
CN-112142757-A | Five-membered nitrogen-containing heteroaryl substituted pyrimidinedione compound and application thereof | 20200929 |
PMID | Publication Date | Title | Journal |
22568036 | 20120301 | TLC determination of meloxicam in tablets and after acidic and alkaline hydrolysis | Acta poloniae pharmaceutica |
19939460 | 20100201 | Trans-cis-cis-[RuCl2(DMSO)2(2-amino-5-methyl-thiazole)2], (PMRu52), a novel ruthenium(II) compound acting as a strong inhibitor of cathepsin B | Journal of inorganic biochemistry |
19608424 | 20090815 | Characterization and DNA-interaction studies of 1,1-dicyano-2,2-ethylene dithiolate Ni(II) mixed-ligand complexes with 2-amino-5-methyl thiazole, 2-amino-2-thiazoline and imidazole. Crystal structure of [Ni(i-MNT)(2a-5mt)(2)] | Bioorganic & medicinal chemistry |
19318255 | 20090415 | Synthesis, characterization, toxicity, cytogenetic and in vivo antitumor studies of 1,1-dithiolate Cu(II) complexes with di-, tri-, tetra- amines and 1,3-thiazoles. Structure-activity correlation | Bioorganic & medicinal chemistry |
21581639 | 20081220 | 2-(4-Chloro-phen-yl)-3-methyl-N-(5-methyl-thia-zol-2-yl)butanamide | Acta crystallographica. Section E, Structure reports online |
Complexity: | 66.7 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 114.02516937 |
Formal Charge: | 0 |
Heavy Atom Count: | 7 |
Hydrogen Bond Acceptor Count: | 3 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 114.02516937 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 67.2 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1 |
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Oxazole/Thiazole
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