2-Amino-5-bromoquinoline - CAS 347146-12-7
Catalog: |
BB022254 |
Product Name: |
2-Amino-5-bromoquinoline |
CAS: |
347146-12-7 |
Synonyms: |
5-bromo-2-quinolinamine; 5-bromoquinolin-2-amine |
IUPAC Name: | 5-bromoquinolin-2-amine |
Description: | 2-Amino-5-bromoquinoline (CAS# 347146-12-7 ) is a useful research chemical. |
Molecular Weight: | 223.07 |
Molecular Formula: | C9H7BrN2 |
Canonical SMILES: | C1=CC2=C(C=CC(=N2)N)C(=C1)Br |
InChI: | InChI=1S/C9H7BrN2/c10-7-2-1-3-8-6(7)4-5-9(11)12-8/h1-5H,(H2,11,12) |
InChI Key: | KBQIVWNPOZQTTE-UHFFFAOYSA-N |
Appearance: | Solid |
LogP: | 2.50960 |
GHS Hazard Statement: | H302 (100%): Harmful if swallowed [Warning Acute toxicity, oral]; H315 (100%): Causes skin irritation [Warning Skin corrosion/irritation]; H319 (100%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]; H335 (100%): May cause respiratory irritation [Warning Specific target organ toxicity, single exposure; Respiratory tract irritation] |
Precautionary Statement: | P261, P264, P264+P265, P270, P271, P280, P301+P317, P302+P352, P304+P340, P305+P351+P338, P319, P321, P330, P332+P317, P337+P317, P362+P364, P403+P233, P405, and P501 |
Signal Word: | Warning |
Publication Number | Title | Priority Date |
CN-107722969-A | A kind of organic electroluminescent compounds | 20160811 |
JP-2016056142-A | Combination of PDE10A inhibitor and antipsychotic | 20140911 |
JP-2016056143-A | Drugs that improve behavioral and psychological symptoms of dementia | 20140911 |
EP-2975037-A1 | Benzothiophene derivative | 20130315 |
JP-WO2014142322-A1 | Benzothiophene derivatives | 20130315 |
PMID | Publication Date | Title | Journal |
21707077 | 20110825 | From fragment screening to in vivo efficacy: optimization of a series of 2-aminoquinolines as potent inhibitors of beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) | Journal of medicinal chemistry |
Complexity: | 163 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 221.97926 |
Formal Charge: | 0 |
Heavy Atom Count: | 12 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 221.97926 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 38.9 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 2.5 |
Online Inquiry
Customer Support
Customer Centered
Related Functional Groups
Amines and Anilines
Customers Also Viewed
INDUSTRY LEADERS TRUST OUR PRODUCTS