2-Amino-5-bromopyridine - CAS 1072-97-5
Catalog: |
BB002045 |
Product Name: |
2-Amino-5-bromopyridine |
CAS: |
1072-97-5 |
Synonyms: |
2-Pyridinamine, 5-bromo-; 5-Bromo-2-pyridinamine; Pyridine, 2-amino-5-bromo-; 5-Bromo-2-aminopyridine; 5-Bromopyridin-2-ylamine; NSC 26282 |
IUPAC Name: | 5-bromopyridin-2-amine |
Description: | 2-Amino-5-bromopyridine (CAS# 1072-97-5) is a compound useful in organic synthesis. A substituted aniline with radioprotective activity. A novel inhibitor of nitric oxide synthases. |
Molecular Weight: | 173.01 |
Molecular Formula: | C5H5BrN2 |
Canonical SMILES: | C1=CC(=NC=C1Br)N |
InChI: | InChI=1S/C5H5BrN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8) |
InChI Key: | WGOLHUGPTDEKCF-UHFFFAOYSA-N |
Boiling Point: | 230.9±20.0°C at 760 mmHg |
Melting Point: | 137°C |
Purity: | ≥95% |
Density: | 1.710±0.06 g/cm3 |
Solubility: | Soluble in Chloroform, Ethyl Acetate, Methanol, Water (Slightly) |
Appearance: | White to Beige Crystalline Solid |
Storage: | Store at RT under inert atmosphere |
MDL: | MFCD00006323 |
LogP: | 2.00750 |
GHS Hazard Statement: | H301 (93.53%): Toxic if swallowed [Danger Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P310, P302+P352, P304+P340, P305+P351+P338, P312, P321, P330, P332+P313, P337+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-113461603-A | Synthetic method of medicine raw material 2, 5-dibromopyridine | 20210701 |
CN-113354576-A | Preparation method of ortho alkoxy substituted pyridine compound | 20210628 |
CN-113429340-A | Method for preparing 4- (6-aminopyridine-3-yl) piperazine-1-carboxylic acid tert-butyl ester | 20210526 |
CN-112575044-A | Method for preparing CDK4/6 inhibitor key intermediate by chemical-enzymatic method | 20201229 |
CN-112608299-A | Synthesis method of 4- (6-aminopyridine-3-yl) piperidine-1-tert-butyl formate | 20201224 |
PMID | Publication Date | Title | Journal |
22590293 | 20120501 | 5-Bromo-N-(3,4-dimeth-oxy-benz-yl)pyridin-2-amine | Acta crystallographica. Section E, Structure reports online |
21913331 | 20111209 | Identification of inhibitors of the Leishmania cdc2-related protein kinase CRK3 | ChemMedChem |
21754117 | 20110401 | N,N'-Bis(5-bromo-pyridin-2-yl)methane-diamine | Acta crystallographica. Section E, Structure reports online |
21179398 | 20100901 | PI3Kα inhibitors that inhibit metastasis | Oncotarget |
21588738 | 20100828 | 2-Amino-5-bromo-pyridinium 3-carb-oxy-4-hy-droxy-benzene-sulfonate | Acta crystallographica. Section E, Structure reports online |
Complexity: | 76.8 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 171.96361 |
Formal Charge: | 0 |
Heavy Atom Count: | 8 |
Hydrogen Bond Acceptor Count: | 2 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 171.96361 |
Rotatable Bond Count: | 0 |
Topological Polar Surface Area: | 38.9 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 1.2 |
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