2-Amino-5-bromo-3-methoxypyrazine - CAS 5900-13-0
Catalog: |
BB030226 |
Product Name: |
2-Amino-5-bromo-3-methoxypyrazine |
CAS: |
5900-13-0 |
Synonyms: |
5-bromo-3-methoxypyrazin-2-amine |
IUPAC Name: | 5-bromo-3-methoxypyrazin-2-amine |
Description: | 2-Amino-5-bromo-3-methoxypyrazine (CAS# 5900-13-0) is an intermediate in the preparation of N-pyrazinylbenzenesulfonamides used in treatment of chemokine mediated diseases such as asthma. |
Molecular Weight: | 204.02 |
Molecular Formula: | C5H6BrN3O |
Canonical SMILES: | COC1=NC(=CN=C1N)Br |
InChI: | InChI=1S/C5H6BrN3O/c1-10-5-4(7)8-2-3(6)9-5/h2H,1H3,(H2,7,8) |
InChI Key: | QDFJJHGAODFQMN-UHFFFAOYSA-N |
Boiling Point: | 262 °C |
Density: | 1.723 g/cm3 |
MDL: | MFCD08275726 |
LogP: | 1.41110 |
GHS Hazard Statement: | H302 (97.62%): Harmful if swallowed [Warning Acute toxicity, oral] |
Precautionary Statement: | P261, P264, P270, P271, P280, P301+P312, P302+P352, P304+P340, P305+P351+P338, P310, P312, P321, P330, P332+P313, P362, P403+P233, P405, and P501 |
Signal Word: | Danger |
Publication Number | Title | Priority Date |
CN-113348170-A | Biphenyl derivative inhibitor, preparation method and application thereof | 20200103 |
WO-2021136354-A1 | Biphenyl derivative inhibitor, preparation method therefor and use thereof | 20200103 |
WO-2021129584-A1 | Pd-l1 antagonist compound | 20191226 |
WO-2021126729-A1 | Prmt5 inhibitors | 20191217 |
WO-2020263980-A1 | Imidazo[1,2-a]pyridinyl derivatives and their use in the treatment of disease | 20190627 |
Complexity: | 113 |
Compound Is Canonicalized: | Yes |
Covalently-Bonded Unit Count: | 1 |
Defined Atom Stereocenter Count: | 0 |
Defined Bond Stereocenter Count: | 0 |
Exact Mass: | 202.96942 |
Formal Charge: | 0 |
Heavy Atom Count: | 10 |
Hydrogen Bond Acceptor Count: | 4 |
Hydrogen Bond Donor Count: | 1 |
Isotope Atom Count: | 0 |
Monoisotopic Mass: | 202.96942 |
Rotatable Bond Count: | 1 |
Topological Polar Surface Area: | 61 Å2 |
Undefined Atom Stereocenter Count: | 0 |
Undefined Bond Stereocenter Count: | 0 |
XLogP3: | 0.8 |
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